Functionalized ionic liquids catalyzed direct aldol reactions

doi:10.1016/j.tet.2006.12.079

CORC > 化学研究所 > 中国科学院化学研究所

	Functionalized ionic liquids catalyzed direct aldol reactions
	Luo, Sanzhong ; Mi, Xueling ; Zhang, Long ; Liu, Song ; Xu, Hui ; Cheng, Jin-Pei
刊名	TETRAHEDRON
	2007-02-26
卷号	63 期号:9 页码:1923-1930
关键词	Functionalized Ionic Liquids Organocatalyst Direct Aldol Reaction
ISSN号	0040-4020
DOI	10.1016/j.tet.2006.12.079
英文摘要	A series of functionalized ionic liquids (FILs) incorporated with chiral-pyrrolidine unit have been synthesized and tested as reusable organocatalysts for direct aldol reactions. FIL 1b in combination with acetic acid and water as additives could effectively catalyze direct aldol reactions of various ketone donors in high yields and the FIL catalyst was easily recycled and reused for six times with slight reduction in activity. Based on experimental observations as well as previous reports, we proposed that the reactions occurred via syn-enamine intermediate and the ionic-liquid moiety in the FIL provides some space shielding for the participating aldehyde acceptors that accounts for the modest enantioselectivities observed in the reactions. (c) 2007 Elsevier Ltd. All rights reserved.
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000244406500005
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/61333]
专题	中国科学院化学研究所
通讯作者	Luo, Sanzhong
作者单位	1.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100080, Peoples R China 2.Nankai Univ, Dept Chem, Tianjin 300071, Peoples R China 3.Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China
推荐引用方式 GB/T 7714	Luo, Sanzhong,Mi, Xueling,Zhang, Long,et al. Functionalized ionic liquids catalyzed direct aldol reactions[J]. TETRAHEDRON,2007,63(9):1923-1930.
APA	Luo, Sanzhong,Mi, Xueling,Zhang, Long,Liu, Song,Xu, Hui,&Cheng, Jin-Pei.(2007).Functionalized ionic liquids catalyzed direct aldol reactions.TETRAHEDRON,63(9),1923-1930.
MLA	Luo, Sanzhong,et al."Functionalized ionic liquids catalyzed direct aldol reactions".TETRAHEDRON 63.9(2007):1923-1930.