Synthesis and characterization of novel poly(ester carbonate)s based on pentaerythritol

doi:10.1002/pola.21941

CORC > 化学研究所 > 中国科学院化学研究所

	Synthesis and characterization of novel poly(ester carbonate)s based on pentaerythritol
	Xie, Zhigang ; Lu, Changhai ; Chen, Xuesi ; Chen, Li ; Wang, Yu ; Hu, Xiuli ; Shi, Quan ; Jing, Xiabin
刊名	JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
	2007-05-01
卷号	45 期号:9 页码:1737-1745
关键词	Biodegradable Functionalization Of Polymers Pentaerythritol Polycarbonates Polylactide
ISSN号	0887-624X
DOI	10.1002/pola.21941
英文摘要	Novel poly(ester carbonate)s were synthesized by the ring-opening polymerization Of L-lactide and functionalized carbonate monomer 9-phenyl-2,4,8,10-tetraoxaspiro[5,5]undecan-3-one derived from pentaerythritol with diethyl zinc as an initiator. H-1 NMR analysis revealed that the carbonate content in the copolymer was almost equal to that in the feed. DSC results indicated that T-g of the copolymer increased with increasing carbonate content in the copolymer. Moreover, the protecting benzylidene groups in the copolymer poly(L-lactide-co-9-phenyl-2,4,8,10-tetraoxaspiro[5,5]undecan-3-one) were removed by hydrogenation with palladium hydroxide on activated charcoal as a catalyst to give a functional copolymer, poly(L-lactide-co-2,2-dihydroxylmethyl-propylene carbonate), containing pendant primary hydroxyl groups. Complete deprotection was confirmed by H-1 NMR and FTIR spectroscopy. The in vitro degradation rate of the deprotected copolymers was faster than that of the protected copolymers in the presence of proteinase K. The cell morphology and viability on a copolymer film evaluated with ECV-304 cells showed that poly(ester carbonate)s derived from pentaerythritol are good biocompatible materials suitable for biomedical applications. (c) 2007 Wiley Periodicals, Inc.
语种	英语
出版者	JOHN WILEY & SONS INC
WOS记录号	WOS:000245830000016
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/60957]
专题	中国科学院化学研究所
通讯作者	Jing, Xiabin
作者单位	1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Xie, Zhigang,Lu, Changhai,Chen, Xuesi,et al. Synthesis and characterization of novel poly(ester carbonate)s based on pentaerythritol[J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY,2007,45(9):1737-1745.
APA	Xie, Zhigang.,Lu, Changhai.,Chen, Xuesi.,Chen, Li.,Wang, Yu.,...&Jing, Xiabin.(2007).Synthesis and characterization of novel poly(ester carbonate)s based on pentaerythritol.JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY,45(9),1737-1745.
MLA	Xie, Zhigang,et al."Synthesis and characterization of novel poly(ester carbonate)s based on pentaerythritol".JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY 45.9(2007):1737-1745.