Electrospinning of hyaluronic acid (HA) and HA/gelatin blends

doi:10.1002/marc.200500726

CORC > 化学研究所 > 中国科学院化学研究所

	Electrospinning of hyaluronic acid (HA) and HA/gelatin blends
	Li, JX ; He, AH ; Han, CC ; Fang, DF ; Hsiao, BS ; Chu, B
刊名	MACROMOLECULAR RAPID COMMUNICATIONS
	2006-01-23
卷号	27 期号:2 页码:114-120
关键词	Electrospinning Gelatin (Ge) Hyaluronic Acid (Ha) Nanofibers
ISSN号	1022-1336
DOI	10.1002/marc.200500726
英文摘要	In the present study, electrospinning of hyaluronic acid (HA) and hyaluronic acid/gelatin (HA-GE) blends in N,N-dimethylformamide (DMF)/water-mixed solvents have been investigated. When the volume ratio of DMF to water was in the range of 1.5-0.5, HA solutions Could be electrospun into fibrous membranes successfully. The average diameter of HA fibers was about 200 rim. The HA-GE composite nanofibrous membranes with varied HA/GE weight ratio in the range of 100/20-100/100 have also been Successfully fabricated. The average diameter of HA-GE fibers was in the range of 190-500 rim. The decrease in surface tension could promote fiber formation. Thus, an introduction of DMF that could decrease the Surface tension distinctively, Without significant change or increase in viscosity of the solution. could bypass the use of blowing-assisted electrospinning. Our postulated Picture is that the lower surface tension could help the ejection of stream with relatively high viscosity and reduce or prevent the droplet formation during the spinning process.
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000235272800004
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/59167]
专题	中国科学院化学研究所
通讯作者	He, AH
作者单位	1.Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Joint Lab Polymer Sci & Mat, Beijing 100080, Peoples R China 2.SUNY Stony Brook, Dept Chem, Stony Brook, NY 11794 USA 3.STAR, Stony Brook, NY 11794 USA
推荐引用方式 GB/T 7714	Li, JX,He, AH,Han, CC,et al. Electrospinning of hyaluronic acid (HA) and HA/gelatin blends[J]. MACROMOLECULAR RAPID COMMUNICATIONS,2006,27(2):114-120.
APA	Li, JX,He, AH,Han, CC,Fang, DF,Hsiao, BS,&Chu, B.(2006).Electrospinning of hyaluronic acid (HA) and HA/gelatin blends.MACROMOLECULAR RAPID COMMUNICATIONS,27(2),114-120.
MLA	Li, JX,et al."Electrospinning of hyaluronic acid (HA) and HA/gelatin blends".MACROMOLECULAR RAPID COMMUNICATIONS 27.2(2006):114-120.