Hydrophilic block copolymer aggregation in solution induced by selective threading of cyclodextrins

doi:10.1002/macp.200600144

CORC > 化学研究所 > 中国科学院化学研究所

	Hydrophilic block copolymer aggregation in solution induced by selective threading of cyclodextrins
	Huang, Jin ; Ren, Lixia ; Zhu, Hui ; Chen, Yongming
刊名	MACROMOLECULAR CHEMISTRY AND PHYSICS
	2006-10-02
卷号	207 期号:19 页码:1764-1772
关键词	Block Copolymers Inclusion Chemistry Self-assembly
ISSN号	1022-1352
DOI	10.1002/macp.200600144
英文摘要	The inclusion of polymer chains by cyclodextrins (CDs) may generate column-like supramolecules. Herein, we report that the selective threading of cyclodextrin rings onto one segment of a double hydrophilic diblock copolymer in water generates spherical aggregates. Poly(ethylene oxide)-blockpoly((dimethylamino)ethyl methacrylate) (PEO-b-PDMA) may dissolve in water to form a homogeneous solution. However, when alpha-CDs are introduced, they thread onto the PEO segments to form pseudopolyrotaxanes, which tend to aggregate. Instead of forming a precipitate, novel supramolecular particles are generated which are attributed to the stabilization of the soluble PDMA segments. The organization process and the assembly structure were characterized by dynamic fight scattering, X-ray diffraction, electron microscopy and 1D NOE NMR spectra. Such novel particles are biocompatible and could have potential applications as biomedical and stimulus-response materials.
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000241288900007
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/58623]
专题	中国科学院化学研究所
通讯作者	Chen, Yongming
作者单位	1.Chinese Acad Sci, Inst Chem, Joint Lab Polymer Sci & Mat, State Key Lab Polymer Phys & Chem, Beijing 100080, Peoples R China 2.Wuhan Univ Technol, Coll Chem Engn, Wuhan 430070, Peoples R China
推荐引用方式 GB/T 7714	Huang, Jin,Ren, Lixia,Zhu, Hui,et al. Hydrophilic block copolymer aggregation in solution induced by selective threading of cyclodextrins[J]. MACROMOLECULAR CHEMISTRY AND PHYSICS,2006,207(19):1764-1772.
APA	Huang, Jin,Ren, Lixia,Zhu, Hui,&Chen, Yongming.(2006).Hydrophilic block copolymer aggregation in solution induced by selective threading of cyclodextrins.MACROMOLECULAR CHEMISTRY AND PHYSICS,207(19),1764-1772.
MLA	Huang, Jin,et al."Hydrophilic block copolymer aggregation in solution induced by selective threading of cyclodextrins".MACROMOLECULAR CHEMISTRY AND PHYSICS 207.19(2006):1764-1772.