Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1

doi:10.1039/c3cc45905e

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	Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1
	Xi, Zhaoyong 1,2; Guo, Wei 3; Tian, Changlin 4; Wang, Fuyi 3; Liu, Yangzhong 1,2
刊名	CHEMICAL COMMUNICATIONS
	2013
卷号	49 期号:95 页码:11197-11199
ISSN号	1359-7345
DOI	10.1039/c3cc45905e
英文摘要	Cu(I) binding promotes the platination of Atox1, although cisplatin binds to the copper coordination sites. In addition, Cu(I) binding enhances the competition of Atox1 with DTT in the reaction of cisplatin. These results indicate that cuprous ions could regulate the cellular trafficking of cisplatin.
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000326741200019
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/54247]
专题	中国科学院化学研究所
通讯作者	Wang, Fuyi
作者单位	1.Univ Sci & Technol China, CAS Key Lab Soft Matter Chem, Hefei 230026, Anhui, Peoples R China 2.Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China 3.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, CAS Key Lab Analyt Chem Living Biosyst, Beijing 100080, Peoples R China 4.Univ Sci & Technol China, Sch Life Sci, Hefei Natl Lab Microscale Phys Sci, Hefei 230026, Anhui, Peoples R China
推荐引用方式 GB/T 7714	Xi, Zhaoyong,Guo, Wei,Tian, Changlin,et al. Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1[J]. CHEMICAL COMMUNICATIONS,2013,49(95):11197-11199.
APA	Xi, Zhaoyong,Guo, Wei,Tian, Changlin,Wang, Fuyi,&Liu, Yangzhong.(2013).Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1.CHEMICAL COMMUNICATIONS,49(95),11197-11199.
MLA	Xi, Zhaoyong,et al."Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1".CHEMICAL COMMUNICATIONS 49.95(2013):11197-11199.