Surfactant-dispersed nanodiamond: biocompatibility evaluation and drug delivery applications

doi:10.1039/c3tx50021g

CORC > 化学研究所 > 中国科学院化学研究所

	Surfactant-dispersed nanodiamond: biocompatibility evaluation and drug delivery applications
	Zhang, Xiaoyong 1; Wang, Shiqi 1; Liu, Meiying 2; Hui, Junfeng 1; Yang, Bin 1; Tao, Lei 1; Wei, Yen 1
刊名	TOXICOLOGY RESEARCH
	2013
卷号	2 期号:5 页码:335-342
ISSN号	2045-452X
DOI	10.1039/c3tx50021g
英文摘要	Effective dispersion of nanodiamond (ND) in aqueous media especially in the physiological solution is of significant importance for its biomedical applications. Herein, the effect of surfactants on the water dispersibility of ND were investigated. On the basis of the dispersion results, biocompatibility as well as utilization of zwitterionic surfactant (lecithin) dispersed ND for intracellular delivery of doxorubicin hydrochloride were explored. We demonstrated that ND nanoparticles displayed enhanced dispersibility in both water and physiological solution in the present of lecithin. Given its facile, effective and low-cost features, the method for dispersion of ND nanoparticles described in this work will contribute significantly to the practical applications of ND.
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000322737600006
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/53731]
专题	中国科学院化学研究所
通讯作者	Zhang, Xiaoyong
作者单位	1.Tsinghua Univ, Dept Chem, Beijing 100084, Peoples R China 2.Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, BNLMS,Lab New Mat, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Xiaoyong,Wang, Shiqi,Liu, Meiying,et al. Surfactant-dispersed nanodiamond: biocompatibility evaluation and drug delivery applications[J]. TOXICOLOGY RESEARCH,2013,2(5):335-342.
APA	Zhang, Xiaoyong.,Wang, Shiqi.,Liu, Meiying.,Hui, Junfeng.,Yang, Bin.,...&Wei, Yen.(2013).Surfactant-dispersed nanodiamond: biocompatibility evaluation and drug delivery applications.TOXICOLOGY RESEARCH,2(5),335-342.
MLA	Zhang, Xiaoyong,et al."Surfactant-dispersed nanodiamond: biocompatibility evaluation and drug delivery applications".TOXICOLOGY RESEARCH 2.5(2013):335-342.