Dual-Cargo Selectively Controlled Release Based on a pH-Responsive Mesoporous Silica System

doi:10.1002/cphc.201402732

CORC > 化学研究所 > 中国科学院化学研究所

	Dual-Cargo Selectively Controlled Release Based on a pH-Responsive Mesoporous Silica System
	Gui, Wanyuan 1; Wang, Wenqian 1; Jiao, Xiangyu 1; Chen, Lifeng 2; Wen, Yongqiang 1; Zhang, Xueji 1
刊名	CHEMPHYSCHEM
	2015-02-23
卷号	16 期号:3 页码:607-613
关键词	Drug Delivery Mesoporous Materials Nanostructures Sensors Sol-gel Processes
ISSN号	1439-4235
DOI	10.1002/cphc.201402732
英文摘要	A pH-controlled delivery system based on mesoporous silica nanoparticles (MSNs) was constructed for dual-cargo selective release. To achieve a better controlled-release effect, a modified sol-gel method was employed to obtain MSNs with tunable particle and pore sizes. The systems selectively released different kinds of cargo when stimulated by different pH values. At the lower pH value (pH 2.0) only one kind of cargo was released from the MSNs, whereas at a higher pH value (pH 7.0) only the other kind of cargo was released from the MSNs. The multi-cargo delivery system has brought the concept of selective release to new advances in the field of functional nanodevices and allows more accurate and controllable delivery of specific cargoes, which is expected to have promising applications in nanomedicine.
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000349964000015
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/53331]
专题	中国科学院化学研究所
通讯作者	Wen, Yongqiang
作者单位	1.Univ Sci & Technol Beijing, Dept Chem & Biol Engn, Beijing 100083, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Gui, Wanyuan,Wang, Wenqian,Jiao, Xiangyu,et al. Dual-Cargo Selectively Controlled Release Based on a pH-Responsive Mesoporous Silica System[J]. CHEMPHYSCHEM,2015,16(3):607-613.
APA	Gui, Wanyuan,Wang, Wenqian,Jiao, Xiangyu,Chen, Lifeng,Wen, Yongqiang,&Zhang, Xueji.(2015).Dual-Cargo Selectively Controlled Release Based on a pH-Responsive Mesoporous Silica System.CHEMPHYSCHEM,16(3),607-613.
MLA	Gui, Wanyuan,et al."Dual-Cargo Selectively Controlled Release Based on a pH-Responsive Mesoporous Silica System".CHEMPHYSCHEM 16.3(2015):607-613.