Strain-promoted azide-alkyne cycloaddition "click" as a conjugation tool for building topological polymers

doi:10.1016/j.polymer.2014.08.003

CORC > 化学研究所 > 中国科学院化学研究所

	Strain-promoted azide-alkyne cycloaddition "click" as a conjugation tool for building topological polymers
	Wang, Shuangshuang 1; Yang, Xiaoke 1; Zhu, Wen 1; Zou, Lei 1; Zhang, Ke 1; Chen, Yongming 1,2; Xi, Fu 1
刊名	POLYMER
	2014-09-15
卷号	55 期号:19 页码:4812-4819
关键词	Click Reaction Star Polymers Strain-promoted Azide-alkyne Cycloaddition
ISSN号	0032-3861
DOI	10.1016/j.polymer.2014.08.003
英文摘要	Strain-promoted azide-alkyne cycloaddition "click" reaction (SPAAC) was successfully used as a tool in synthesis of star polymers by grafting onto approach. The application of SPAAC method in star polymer synthesis was investigated for coupling reaction of the dibenzocyclooctyne (DIBO) end group of polystyrene (PS) and poly(ethylene glycol) (PEG) with coupling agents bearing 2, 3, or 4 azido groups. Firstly, well-defined linear DIBO-terminated PS was obtained by atom transfer radical polymerization (ATRP) of styrene using a DIBO containing ATRP initiator and linear DIBO-terminated PEG was obtained by terminal functionalization of PEG monomethyl ether (PEG-OH). Then a series of star PS and PEG bearing two, three and four arms were prepared respectively by subjecting SPAAC coupling reaction between the linear polymer-DIBO and the azido tethered core molecules at 30 degrees C without catalyst. The obtained star PS showed a well-defined structure after fractional precipitation to remove slightly excess linear polymers, and all the star polymers were characterized via Fourier transform infrared spectroscopy (FTIR), H-1 nuclear magnetic resonance spectroscopy (H-1 NMR), size exclusion chromatography (SEC) and matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS). (C) 2014 Elsevier Ltd. All rights reserved.
语种	英语
出版者	ELSEVIER SCI LTD
WOS记录号	WOS:000341906100002
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/53149]
专题	中国科学院化学研究所
通讯作者	Chen, Yongming
作者单位	1.Chinese Acad Sci, Inst Chem, Lab Polymer Phys & Chem, Beijing 100190, Peoples R China 2.Sun Yat Sen Univ, Sch Chem & Chem Engn, Key Lab Polymer Composite & Funct Mat, Minist Educ, Guangzhou 510275, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Wang, Shuangshuang,Yang, Xiaoke,Zhu, Wen,et al. Strain-promoted azide-alkyne cycloaddition "click" as a conjugation tool for building topological polymers[J]. POLYMER,2014,55(19):4812-4819.
APA	Wang, Shuangshuang.,Yang, Xiaoke.,Zhu, Wen.,Zou, Lei.,Zhang, Ke.,...&Xi, Fu.(2014).Strain-promoted azide-alkyne cycloaddition "click" as a conjugation tool for building topological polymers.POLYMER,55(19),4812-4819.
MLA	Wang, Shuangshuang,et al."Strain-promoted azide-alkyne cycloaddition "click" as a conjugation tool for building topological polymers".POLYMER 55.19(2014):4812-4819.