Fabrication of water-dispersible and biocompatible red fluorescent organic nanoparticles via PEGylation of aggregate induced emission enhancement dye and their cell imaging applications

doi:10.1016/j.colsurfb.2013.09.031

CORC > 化学研究所 > 中国科学院化学研究所

	Fabrication of water-dispersible and biocompatible red fluorescent organic nanoparticles via PEGylation of aggregate induced emission enhancement dye and their cell imaging applications
	Zhang, Xiaoyong 1,2,3; Zhang, Xiqi 2,3; Yang, Bin 2,3; Zhang, Yaling 2,3; Liu, Meiying 4; Liu, Wanyun 1; Chen, Yiwang 1; Wei, Yen 2,3
刊名	COLLOIDS AND SURFACES B-BIOINTERFACES
	2014
卷号	113 页码:435-441
关键词	Fluorescent Organic Nanoparticles Cyano-substituted Diarylethene Derivate Dye Pegylation Aggregation Induced Emission Cell Imaging Biocompatibility
ISSN号	0927-7765
DOI	10.1016/j.colsurfb.2013.09.031
英文摘要	PEGylated red fluorescent organic nanoparticles (FONs) with aggregate induced emission enhancement (AIEE) properties have been prepared via self assembly of a cyano-substituted diarylethene derivate dye (C18-R) and synthetic copolymers, which were obtained by reversible addition-fragmentation chain transfer (RAFT) polymerization using stearyl methacrylate and poly(ethylene glycol) methacrylate as monomers. Thus obtained FONs were characterized by a series of techniques including transmission electron microscopy, Fourier transform infrared spectroscopy and fluorescent spectroscopy. To explore their potential biomedical applications, biocompatibility and cell uptake behavior of these red FONs were subsequently investigated. We demonstrated that FONs showed uniform morphology, suitable particle size (70-90 nm), high water dispersibility, strong red fluorescence and excellent biocompatibility, making them promising for bioimaging applications. Crown Copyright (C) 2013 Published by Elsevier B.V. All rights reserved.
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000331670200055
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/52719]
专题	中国科学院化学研究所
通讯作者	Zhang, Xiaoyong
作者单位	1.Nanchang Univ, Inst Polymer, Dept Chem, Nanchang 330031, Peoples R China 2.Minist Educ, Dept Chem, Taipei City, Peoples R China 3.Minist Educ, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Taipei City, Peoples R China 4.Chinese Acad Sci, Inst Chem, New Mat Lab, Key Lab Organ Solids,BNLMS, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Xiaoyong,Zhang, Xiqi,Yang, Bin,et al. Fabrication of water-dispersible and biocompatible red fluorescent organic nanoparticles via PEGylation of aggregate induced emission enhancement dye and their cell imaging applications[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2014,113:435-441.
APA	Zhang, Xiaoyong.,Zhang, Xiqi.,Yang, Bin.,Zhang, Yaling.,Liu, Meiying.,...&Wei, Yen.(2014).Fabrication of water-dispersible and biocompatible red fluorescent organic nanoparticles via PEGylation of aggregate induced emission enhancement dye and their cell imaging applications.COLLOIDS AND SURFACES B-BIOINTERFACES,113,435-441.
MLA	Zhang, Xiaoyong,et al."Fabrication of water-dispersible and biocompatible red fluorescent organic nanoparticles via PEGylation of aggregate induced emission enhancement dye and their cell imaging applications".COLLOIDS AND SURFACES B-BIOINTERFACES 113(2014):435-441.