Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes

doi:10.1002/anie.201309449

CORC > 化学研究所 > 中国科学院化学研究所

	Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes
	Yue, Guozong 3; Zhang, Yun 3; Fang, Lichao 3; Li, Chuang-chuang 3; Luo, Tuoping 1,2; Yang, Zhen 1,2,3
刊名	ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
	2014-02-10
卷号	53 期号:7 页码:1837-1840
关键词	Cascade Reaction Cyclization Gold Natural Products Total Synthesis
ISSN号	1433-7851
DOI	10.1002/anie.201309449
英文摘要	The cladiellin family of natural products, which includes molecules with various biological activities, continues to invite new synthetic studies. A gold-catalyzed tandem reaction of 1,7-diynes to construct the 6-5-bicyclic ring systems that are present in a number of natural products was developed. This reaction was applied as the key step to realize the formal and total syntheses of nine members of the cladiellin family in an enantio- and diastereoselective manner. This modular and efficient approach could also be used for the construction of other cladiellins, as well as their analogues, for follow-up studies.
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000330680400014
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/52607]
专题	中国科学院化学研究所
通讯作者	Luo, Tuoping
作者单位	1.Peking Univ, Key Lab Bioorgan Chem & Mol Engn, Minist Educ, Beijing 100871, Peoples R China 2.Peking Univ, Peking Tsinghua Ctr Life Sci, BNLMS, Beijing 100871, Peoples R China 3.Peking Univ, Shenzhen Grad Sch, Lab Chem Genom, Sch Chem Biol & Biotechnol, Shenzhen 518055, Peoples R China
推荐引用方式 GB/T 7714	Yue, Guozong,Zhang, Yun,Fang, Lichao,et al. Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2014,53(7):1837-1840.
APA	Yue, Guozong,Zhang, Yun,Fang, Lichao,Li, Chuang-chuang,Luo, Tuoping,&Yang, Zhen.(2014).Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,53(7),1837-1840.
MLA	Yue, Guozong,et al."Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 53.7(2014):1837-1840.