Hybrid polymer micelles capable of cRGD targeting and pH-triggered surface charge conversion for tumor selective accumulation and promoted uptake | |
Hu, Xiuli1; Guan, Xingang1,2; Li, Jing1; Pei, Qing1,3; Liu, Ming1,3; Xie, Zhigang1; Jing, Xiabin1 | |
刊名 | CHEMICAL COMMUNICATIONS
![]() |
2014-08-21 | |
卷号 | 50期号:65页码:9188-9191 |
ISSN号 | 1359-7345 |
DOI | 10.1039/c4cc04056b |
英文摘要 | This study presents both tumor-targeting ligands (cRGD) and pH-activated surface charge-conversional moiety (imidazole) decorated micelles for Dox delivery. cRGD is expected to induce preferential tumor accumulation, while imidazole switches on positive charge in a tumor acid environment, which leads to enhanced micelle uptake by tumor cells. |
语种 | 英语 |
出版者 | ROYAL SOC CHEMISTRY |
WOS记录号 | WOS:000339930400041 |
内容类型 | 期刊论文 |
源URL | [http://ir.iccas.ac.cn/handle/121111/52339] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Xie, Zhigang |
作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Beihua Univ, Life Sci Res Ctr, Jilin 132013, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Hu, Xiuli,Guan, Xingang,Li, Jing,et al. Hybrid polymer micelles capable of cRGD targeting and pH-triggered surface charge conversion for tumor selective accumulation and promoted uptake[J]. CHEMICAL COMMUNICATIONS,2014,50(65):9188-9191. |
APA | Hu, Xiuli.,Guan, Xingang.,Li, Jing.,Pei, Qing.,Liu, Ming.,...&Jing, Xiabin.(2014).Hybrid polymer micelles capable of cRGD targeting and pH-triggered surface charge conversion for tumor selective accumulation and promoted uptake.CHEMICAL COMMUNICATIONS,50(65),9188-9191. |
MLA | Hu, Xiuli,et al."Hybrid polymer micelles capable of cRGD targeting and pH-triggered surface charge conversion for tumor selective accumulation and promoted uptake".CHEMICAL COMMUNICATIONS 50.65(2014):9188-9191. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论