Suzuki-Miyaura coupling of phosphinoyl-alpha-allenic alcohols with arylboronic acids catalyzed by a palladium complex "on water": an efficient method to generate phosphinoyl 1,3-butadienes and derivatives

doi:10.1039/c4ra12251h

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	Suzuki-Miyaura coupling of phosphinoyl-alpha-allenic alcohols with arylboronic acids catalyzed by a palladium complex "on water": an efficient method to generate phosphinoyl 1,3-butadienes and derivatives
	Liu, Teng 1,2; Dong, Jie 1,2; Cao, Shu-Jun 1,2; Guo, Li-Cheng 1,2; Wu, Lei 1,2,3
刊名	RSC ADVANCES
	2014
卷号	4 期号:106 页码:61722-61726
ISSN号	2046-2069
DOI	10.1039/c4ra12251h
英文摘要	We report here the first palladium-catalyzed Suzuki-Miyaura couplings of phosphinoyl-alpha-allenic alcohols with arylboronic acids "on water" without phase-transfer catalysts or additives. This new methodology provides a novel approach to generate phosphinoyl 1,3-butadienes and derivatives with medium to excellent yields. A mechanism via initial C(sp(3))-OH bond cleavage of the substrate to form pi-allyl-palladium intermediates, and transmetallation with arylboronic acid, followed by reductive elimination to afford the product, is proposed.
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000345656600066
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/51713]
专题	中国科学院化学研究所
通讯作者	Wu, Lei
作者单位	1.Nanjing Agr Univ, Coll Sci, Jiangsu Key Lab Pesticide Sci, Nanjing 210095, Jiangsu, Peoples R China 2.Nanjing Agr Univ, Coll Sci, Dept Chem, Nanjing 210095, Jiangsu, Peoples R China 3.Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Liu, Teng,Dong, Jie,Cao, Shu-Jun,et al. Suzuki-Miyaura coupling of phosphinoyl-alpha-allenic alcohols with arylboronic acids catalyzed by a palladium complex "on water": an efficient method to generate phosphinoyl 1,3-butadienes and derivatives[J]. RSC ADVANCES,2014,4(106):61722-61726.
APA	Liu, Teng,Dong, Jie,Cao, Shu-Jun,Guo, Li-Cheng,&Wu, Lei.(2014).Suzuki-Miyaura coupling of phosphinoyl-alpha-allenic alcohols with arylboronic acids catalyzed by a palladium complex "on water": an efficient method to generate phosphinoyl 1,3-butadienes and derivatives.RSC ADVANCES,4(106),61722-61726.
MLA	Liu, Teng,et al."Suzuki-Miyaura coupling of phosphinoyl-alpha-allenic alcohols with arylboronic acids catalyzed by a palladium complex "on water": an efficient method to generate phosphinoyl 1,3-butadienes and derivatives".RSC ADVANCES 4.106(2014):61722-61726.