Application of "Click" Chemistry to the Construction of Supramolecular Functional Systems

doi:10.1002/ajoc.201300245

CORC > 化学研究所 > 中国科学院化学研究所

	Application of "Click" Chemistry to the Construction of Supramolecular Functional Systems
	Xu, Liang 1,2; Li, Yongjun 1; Li, Yuliang 1
刊名	ASIAN JOURNAL OF ORGANIC CHEMISTRY
	2014-05-01
卷号	3 期号:5 页码:582-602
关键词	Bioactive Macrocycles Click Chemistry Molecular Machines Receptors Triazoles
ISSN号	2193-5807
DOI	10.1002/ajoc.201300245
英文摘要	The aim of this article is to summarize the recent advances in the synthesis of functional systems based on Cu-I-catalyzed azide-alkyne cycloaddition reaction. This reaction has the ability to exclusively afford 1,4-disubstituted 1,2,3-triazoles regioselectively, which have several features. First, such triazoles have a polarized CH bond, which could be used as a H-bond donor. Second, its atom arrangement and electronic properties are similar to those of a peptide bond, making it a candidate for an amide surrogate. Third, it has three nitrogen atoms, two of which could be used as coordinating sites for metal ions. Based on these features, 1,2,3-triazoles have potential applications in the construction of supramolecular functional systems. The design and synthesis strategies for anion receptors, bioactive macrocycles, and molecular machines are reviewed here. And in this scope we focus on foldamer-based receptors, macrocycle-based receptors, macrocyclic carbohydrates, macrocyclic peptides, catenanes, and rotaxanes.
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000335518800001
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/51563]
专题	中国科学院化学研究所
通讯作者	Li, Yongjun
作者单位	1.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, CAS Key Lab Organ Solid, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Xu, Liang,Li, Yongjun,Li, Yuliang. Application of "Click" Chemistry to the Construction of Supramolecular Functional Systems[J]. ASIAN JOURNAL OF ORGANIC CHEMISTRY,2014,3(5):582-602.
APA	Xu, Liang,Li, Yongjun,&Li, Yuliang.(2014).Application of "Click" Chemistry to the Construction of Supramolecular Functional Systems.ASIAN JOURNAL OF ORGANIC CHEMISTRY,3(5),582-602.
MLA	Xu, Liang,et al."Application of "Click" Chemistry to the Construction of Supramolecular Functional Systems".ASIAN JOURNAL OF ORGANIC CHEMISTRY 3.5(2014):582-602.