Electrochemical synthesis and characterization of a novel thiazole-based copolymer and its application in biosensor

doi:10.1016/j.electacta.2011.10.061

CORC > 化学研究所 > 中国科学院化学研究所

	Electrochemical synthesis and characterization of a novel thiazole-based copolymer and its application in biosensor
	Xue, Ying 1; Sheng, Zhonghan 2; Zhao, Hong 1; Wu, Zhijiao 1; Li, Xiangjun 1; He, Yujian 1; Yuan, Zhuobin 1
刊名	ELECTROCHIMICA ACTA
	2012
卷号	59 页码:256-263
关键词	2-aminothiazole 2-amino-4-thiazoleacetic Acid Conjugated Copolymer Biosensor
ISSN号	0013-4686
DOI	10.1016/j.electacta.2011.10.061
英文摘要	A novel copolymer based on 2-aminothiazole (AT) and 2-amino-4-thiazoleacetic acid (ATA) is electrochemically synthesized and then characterized using UV-visible absorption spectroscopy (UV-vis), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and electrochemical techniques. The results confirmed that the obtained polymer was a copolymer rather than a blend or a composite of the respective homopolymers and could improve the electrochemical response of both positively and negatively charged analytes. Therefore, the copolythiazole film was applied to determine ascorbic acid (AA), dopamine (DA) and uric acid (UA). It is found that the peak separating degrees and peak currents of AA, DA and UA at copolythiazole modified electrode were much better than those at bare GCE. Under the optimum conditions, the linear calibration curves were obtained in the range of 10-2000 mu M for AA, 1-150 mu M for DA, 1-180 mu M for UA. The detection limits of AA, DA and UA were 2, 0.04 and 0.4 mu M, respectively (S/N = 3). The practical application of the modified electrode was demonstrated by the determination of UA in urine sample. (C) 2011 Elsevier Ltd. All rights reserved.
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000299911500038
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/49151]
专题	中国科学院化学研究所
通讯作者	Zhao, Hong
作者单位	1.Chinese Acad Sci, Grad Univ, Coll Chem & Chem Engn, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Xue, Ying,Sheng, Zhonghan,Zhao, Hong,et al. Electrochemical synthesis and characterization of a novel thiazole-based copolymer and its application in biosensor[J]. ELECTROCHIMICA ACTA,2012,59:256-263.
APA	Xue, Ying.,Sheng, Zhonghan.,Zhao, Hong.,Wu, Zhijiao.,Li, Xiangjun.,...&Yuan, Zhuobin.(2012).Electrochemical synthesis and characterization of a novel thiazole-based copolymer and its application in biosensor.ELECTROCHIMICA ACTA,59,256-263.
MLA	Xue, Ying,et al."Electrochemical synthesis and characterization of a novel thiazole-based copolymer and its application in biosensor".ELECTROCHIMICA ACTA 59(2012):256-263.