pH- and Redox-Responsive Polysaccharide-Based Microcapsules with Autofluorescence for Biomedical Applications | |
Gao, Liang; Fei, Jinbo; Zhao, Jie; Cui, Wei; Cui, Yue; Li, Junbai | |
刊名 | CHEMISTRY-A EUROPEAN JOURNAL
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2012-03-01 | |
卷号 | 18期号:11页码:3185-3192 |
关键词 | Autofluorescence Drug Delivery Microcapsules Polysaccharide |
ISSN号 | 0947-6539 |
DOI | 10.1002/chem.201103584 |
英文摘要 | Autofluorescent microcapsules were assembled by covalent cross-linking of polysaccharide alginate dialdehyde (ADA) derivative and cystamine dihydrochloride (CM) through a layer-by-layer (LBL) technique. The formulated Schiff base and disulfide bonds render capsules with pH- and redox-responsive properties for pinpointed intracellular delivery based on the physiological difference between intracellular and extracellular environments. This simple and versatile method could be extended to other polysaccharide derivatives for the fabrication of autofluorescent nano- and micromaterials with dual stimuli response for biomedical applications. |
语种 | 英语 |
出版者 | WILEY-V C H VERLAG GMBH |
WOS记录号 | WOS:000300972500014 |
内容类型 | 期刊论文 |
源URL | [http://ir.iccas.ac.cn/handle/121111/47937] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Li, Junbai |
作者单位 | Chinese Acad Sci, Beijing Natl Lab Mol Sci, Ctr Mol Sci, Key Lab Colloid & Interface Sci,Inst Chem, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Gao, Liang,Fei, Jinbo,Zhao, Jie,et al. pH- and Redox-Responsive Polysaccharide-Based Microcapsules with Autofluorescence for Biomedical Applications[J]. CHEMISTRY-A EUROPEAN JOURNAL,2012,18(11):3185-3192. |
APA | Gao, Liang,Fei, Jinbo,Zhao, Jie,Cui, Wei,Cui, Yue,&Li, Junbai.(2012).pH- and Redox-Responsive Polysaccharide-Based Microcapsules with Autofluorescence for Biomedical Applications.CHEMISTRY-A EUROPEAN JOURNAL,18(11),3185-3192. |
MLA | Gao, Liang,et al."pH- and Redox-Responsive Polysaccharide-Based Microcapsules with Autofluorescence for Biomedical Applications".CHEMISTRY-A EUROPEAN JOURNAL 18.11(2012):3185-3192. |
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