pH- and Redox-Responsive Polysaccharide-Based Microcapsules with Autofluorescence for Biomedical Applications

doi:10.1002/chem.201103584

CORC > 化学研究所 > 中国科学院化学研究所

	pH- and Redox-Responsive Polysaccharide-Based Microcapsules with Autofluorescence for Biomedical Applications
	Gao, Liang; Fei, Jinbo; Zhao, Jie; Cui, Wei; Cui, Yue; Li, Junbai
刊名	CHEMISTRY-A EUROPEAN JOURNAL
	2012-03-01
卷号	18 期号:11 页码:3185-3192
关键词	Autofluorescence Drug Delivery Microcapsules Polysaccharide
ISSN号	0947-6539
DOI	10.1002/chem.201103584
英文摘要	Autofluorescent microcapsules were assembled by covalent cross-linking of polysaccharide alginate dialdehyde (ADA) derivative and cystamine dihydrochloride (CM) through a layer-by-layer (LBL) technique. The formulated Schiff base and disulfide bonds render capsules with pH- and redox-responsive properties for pinpointed intracellular delivery based on the physiological difference between intracellular and extracellular environments. This simple and versatile method could be extended to other polysaccharide derivatives for the fabrication of autofluorescent nano- and micromaterials with dual stimuli response for biomedical applications.
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000300972500014
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/47937]
专题	中国科学院化学研究所
通讯作者	Li, Junbai
作者单位	Chinese Acad Sci, Beijing Natl Lab Mol Sci, Ctr Mol Sci, Key Lab Colloid & Interface Sci,Inst Chem, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Gao, Liang,Fei, Jinbo,Zhao, Jie,et al. pH- and Redox-Responsive Polysaccharide-Based Microcapsules with Autofluorescence for Biomedical Applications[J]. CHEMISTRY-A EUROPEAN JOURNAL,2012,18(11):3185-3192.
APA	Gao, Liang,Fei, Jinbo,Zhao, Jie,Cui, Wei,Cui, Yue,&Li, Junbai.(2012).pH- and Redox-Responsive Polysaccharide-Based Microcapsules with Autofluorescence for Biomedical Applications.CHEMISTRY-A EUROPEAN JOURNAL,18(11),3185-3192.
MLA	Gao, Liang,et al."pH- and Redox-Responsive Polysaccharide-Based Microcapsules with Autofluorescence for Biomedical Applications".CHEMISTRY-A EUROPEAN JOURNAL 18.11(2012):3185-3192.