A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes

doi:10.1016/j.bios.2013.03.057

CORC > 化学研究所 > 中国科学院化学研究所

	A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes
	Li, Ruimin 1; Zhen, Mingming 1; Guan, Mirong 1; Chen, Daiqin 1; Zhang, Guoqiang 1; Ge, Jiechao 2; Gong, Ping 3; Wang, Chunru 1; Shu, Chunying 1
刊名	BIOSENSORS & BIOELECTRONICS
	2013-09-15
卷号	47 页码:502-507
关键词	C-60-carboxyfullerenes Peroxidase-like Activity Colorimetric Sensor Glucose
ISSN号	0956-5663
DOI	10.1016/j.bios.2013.03.057
英文摘要	C-60-carboxyfullerene, C-60[C(COOH)(2)](2), has been proven to function as peroxidase mimetics that can catalyze the reaction of peroxidase substrate 3,3',5,5'-tetramethylbenzidine (TMB) in the presence of H2O2 to produce a blue color reaction. Kinetic studies further indicate that C-60[C(COOH)(2)](2) has an even higher affinity to TMB than that of the natural enzyme, horseradish peroxidase (HRP). C-60[C(COOH)(2)](2)/glucose oxidase (GO(x))/TMB system provides a novel colorimetric sensor for glucose and shows good response toward glucose detection over a range of 1.0-40 mu M with a limit of detection 0.5 mu M (3 sigma/slope). Moreover, this sensitive and selective sensor can be successfully applied for the quantitative determination of glucose in human serum. The results indicate that it is a simple, cheap, convenient, highly selective, sensitive, and easy handling colorimetric assay. (C) 2013 Elsevier B.V. All rights reserved.
语种	英语
出版者	ELSEVIER ADVANCED TECHNOLOGY
WOS记录号	WOS:000320481900076
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/46563]
专题	中国科学院化学研究所
通讯作者	Ge, Jiechao
作者单位	1.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Mol Nanostruct & Nanotechnol, Inst Chem, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100190, Peoples R China 3.Peking Univ, Hosp 3, Beijing 100191, Peoples R China
推荐引用方式 GB/T 7714	Li, Ruimin,Zhen, Mingming,Guan, Mirong,et al. A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes[J]. BIOSENSORS & BIOELECTRONICS,2013,47:502-507.
APA	Li, Ruimin.,Zhen, Mingming.,Guan, Mirong.,Chen, Daiqin.,Zhang, Guoqiang.,...&Shu, Chunying.(2013).A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes.BIOSENSORS & BIOELECTRONICS,47,502-507.
MLA	Li, Ruimin,et al."A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes".BIOSENSORS & BIOELECTRONICS 47(2013):502-507.