Antibacterial and Hemocompatibility Switchable Polypropylene Nonwoven Fabric Membrane Surface

doi:10.1021/am401098u

CORC > 化学研究所 > 中国科学院化学研究所

	Antibacterial and Hemocompatibility Switchable Polypropylene Nonwoven Fabric Membrane Surface
	Zhao, Jie; Song, Lingjie; Shi, Qiang; Luan, Shifang; Yin, Jinghua
刊名	ACS APPLIED MATERIALS & INTERFACES
	2013-06-12
卷号	5 期号:11 页码:5260-5268
关键词	Antibacterial Uv-induced Graft Polymerization Polypropylene Nonwoven Fabric Membrane Hemocompatibility Zwitterionic Polymer
ISSN号	1944-8244
DOI	10.1021/am401098u
英文摘要	In this article, a facile approach to fabricate a, biofunctional polypropylene nonwoven fabric membrane (PP NWF) with a switchable surface from antibacterial property to hemocompatibility is presented. In the first step, a cationic carboxybetaine ester monomer, [(2-(methacryboxy) ethyl)]-N,N-dimethylamino-ethylammonium bromide, methyl ester (CABA-1-ester) was synthesized. Subsequently, this monomer was introduced on the PP NWF surface via plasma pretreatment and a UV-induced graft polymerization technique. Finally, a switchable surface from antibacterial property to hemocompatibility was easily realized by hydrolysis of poly(CABA-1-ester) moieties on the PP NWF surface under mild conditions., Surface hydrolysis behaviors under different pH conditions were investigated. These PP NWFs grafted with poly(CABA-1-ester) segments can cause significant suppression of S. aureus proliferation; after hydrolysis, these surfaces covered by poly[(2-(methacryloxy) ethyl)] carboxybetaine (poly(CABA)) chains exhibited obvious reduction in protein adsorption and platelet adhesion, and remarkably enhanced antithrombotic properties. This strategy demonstrated that a switchable PP NWF surface from antibacterial property to hemocompatibility was easily developed by plasma pretreatment and UV-induced surface graft polymerization and that this surface may become an attractive platform for a range of biomedical applications.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000320484000103
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/46513]
专题	中国科学院化学研究所
通讯作者	Yin, Jinghua
作者单位	Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Jie,Song, Lingjie,Shi, Qiang,et al. Antibacterial and Hemocompatibility Switchable Polypropylene Nonwoven Fabric Membrane Surface[J]. ACS APPLIED MATERIALS & INTERFACES,2013,5(11):5260-5268.
APA	Zhao, Jie,Song, Lingjie,Shi, Qiang,Luan, Shifang,&Yin, Jinghua.(2013).Antibacterial and Hemocompatibility Switchable Polypropylene Nonwoven Fabric Membrane Surface.ACS APPLIED MATERIALS & INTERFACES,5(11),5260-5268.
MLA	Zhao, Jie,et al."Antibacterial and Hemocompatibility Switchable Polypropylene Nonwoven Fabric Membrane Surface".ACS APPLIED MATERIALS & INTERFACES 5.11(2013):5260-5268.