Highly enantioselective transfer hydrogenation of racemic alpha-substituted beta-keto sulfonamides via dynamic kinetic resolution

doi:10.1039/c8cc01643g

CORC > 化学研究所 > 中国科学院化学研究所

	Highly enantioselective transfer hydrogenation of racemic alpha-substituted beta-keto sulfonamides via dynamic kinetic resolution
	Xiong, Zhichao 1; Pei, Chengfeng 1; Xue, Peng 1; Lv, Hui 1,2,3; Zhang, Xumu 4
刊名	CHEMICAL COMMUNICATIONS
	2018-04-17
卷号	54 期号:31 页码:3883-3886
ISSN号	1359-7345
DOI	10.1039/c8cc01643g
英文摘要	Highly enantioselective transfer hydrogenation of -keto sulfonamides was developed via dynamic kinetic resolution using a chiral Ru(ii) catalyst with an azeotropic solution of HCO2H/Et3N as a hydrogen donor, affording -substituted -hydroxyl sulfonamides in good yields with excellent diastereo- and enantioselectivities. This method is featured with mild conditions, easy operation, and a broad substrate scope, which make it possible to find wide applications in the synthesis of natural products and biologically active compounds containing the -substituted -hydroxyl sulfonamide core.
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000430022100020
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/46263]
专题	中国科学院化学研究所
通讯作者	Lv, Hui; Zhang, Xumu
作者单位	1.Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Hubei, Peoples R China 2.Wuhan Univ, Coll Chem & Mol Sci, Minist Educ, Engn Res Ctr Organosilicon Cpds & Mat, Wuhan 430072, Hubei, Peoples R China 3.Chinese Acad Sci, Inst Chem, Key Lab Mol Recognit & Funct, Beijing 100190, Peoples R China 4.South Univ Sci & Technol China, Dept Chem, Shenzhen 518055, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Xiong, Zhichao,Pei, Chengfeng,Xue, Peng,et al. Highly enantioselective transfer hydrogenation of racemic alpha-substituted beta-keto sulfonamides via dynamic kinetic resolution[J]. CHEMICAL COMMUNICATIONS,2018,54(31):3883-3886.
APA	Xiong, Zhichao,Pei, Chengfeng,Xue, Peng,Lv, Hui,&Zhang, Xumu.(2018).Highly enantioselective transfer hydrogenation of racemic alpha-substituted beta-keto sulfonamides via dynamic kinetic resolution.CHEMICAL COMMUNICATIONS,54(31),3883-3886.
MLA	Xiong, Zhichao,et al."Highly enantioselective transfer hydrogenation of racemic alpha-substituted beta-keto sulfonamides via dynamic kinetic resolution".CHEMICAL COMMUNICATIONS 54.31(2018):3883-3886.