Bioactive glass sol as a dual function additive for chitosan-alginate hybrid scaffold

doi:10.1016/j.cclet.2018.01.023

CORC > 化学研究所 > 中国科学院化学研究所

	Bioactive glass sol as a dual function additive for chitosan-alginate hybrid scaffold
	Ren, Huihui 1,2; Cui, Yang 1,2; Li, Ailing 1; Qiu, Dong 1,2
刊名	CHINESE CHEMICAL LETTERS
	2018-03-01
卷号	29 期号:3 页码:395-398
关键词	Bioactive Glass Sol Chitosan Alginate Dual Function Additive Bioactivity
ISSN号	1001-8417
DOI	10.1016/j.cclet.2018.01.023
英文摘要	Bioactive glass-chitosan-alginate hybrid scaffolds (BG-C-A scaffolds) were fabricated using BG sol as a dual function additive, which behaves as both bioactive inorganic phase to confer the bioactivity and cross-linker to improve the structural stability and mechanical properties. The microstructure, physicochemical and mechanical properties, in vitro bioactivity and cellular biocompatibility of the scaffolds were investigated. The results indicated that BG component was successfully incorporated into the BG-C-A scaffolds through a facile BG sol-immersing method and the original interconnected microstructure could be well preserved. The obtained BG-C-A scaffolds showed improved mechanical properties and structural stability as compared to C-A scaffolds. At the same time, they presented excellent in vitro bioactivity and cellular compatibility. All these results demonstrated that these BG-C-A scaffolds have promising potential for tissue engineering. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
语种	英语
出版者	ELSEVIER SCIENCE INC
WOS记录号	WOS:000429392800012
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/46105]
专题	中国科学院化学研究所
通讯作者	Qiu, Dong
作者单位	1.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Stare Key Lab Polymer Phys & Chem, CAS Res Educ Ctr Excellence Mol Sci,Inst Chem, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Ren, Huihui,Cui, Yang,Li, Ailing,et al. Bioactive glass sol as a dual function additive for chitosan-alginate hybrid scaffold[J]. CHINESE CHEMICAL LETTERS,2018,29(3):395-398.
APA	Ren, Huihui,Cui, Yang,Li, Ailing,&Qiu, Dong.(2018).Bioactive glass sol as a dual function additive for chitosan-alginate hybrid scaffold.CHINESE CHEMICAL LETTERS,29(3),395-398.
MLA	Ren, Huihui,et al."Bioactive glass sol as a dual function additive for chitosan-alginate hybrid scaffold".CHINESE CHEMICAL LETTERS 29.3(2018):395-398.