Synthesis of Pinacol Arylboronates from Aromatic Amines: A Metal-Free Transformation

doi:10.1021/jo3018878

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	Synthesis of Pinacol Arylboronates from Aromatic Amines: A Metal-Free Transformation
	Qiu, Di; Jin, Liang; Zheng, Zhitong; Meng, He; Mo, Fanyang; Wang, Xi; Zhang, Yan; Wang, Jianbo
刊名	JOURNAL OF ORGANIC CHEMISTRY
	2013-03-01
卷号	78 期号:5 页码:1923-1933
ISSN号	0022-3263
DOI	10.1021/jo3018878
英文摘要	A metal-free borylation process based on Sandmeyer-type transformation using arylamines derivatives as the substrates has been developed. Through optimization of the reaction conditions, this novel conversion can be successfully applied to a wide range of aromatic amines, affording borylation products in moderate to good yields. Various functionalized arylboronates, which are difficult to access by other methods, can be easily obtained with this metal free transformation. Moreover, this transformation can be followed by Suzuki-Miyaura cross coupling without purification of the borylation products, which enhances the practical usefulness of this method. A possible reaction mechanism involving radical species has been proposed.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000315707500027
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/43337]
专题	中国科学院化学研究所
通讯作者	Mo, Fanyang
作者单位	Peking Univ, Coll Chem, Key Lab Bioorgan Chem & Mol Engn, Beijing Natl Lab Mol Sci,Minist Educ, Beijing 100871, Peoples R China
推荐引用方式 GB/T 7714	Qiu, Di,Jin, Liang,Zheng, Zhitong,et al. Synthesis of Pinacol Arylboronates from Aromatic Amines: A Metal-Free Transformation[J]. JOURNAL OF ORGANIC CHEMISTRY,2013,78(5):1923-1933.
APA	Qiu, Di.,Jin, Liang.,Zheng, Zhitong.,Meng, He.,Mo, Fanyang.,...&Wang, Jianbo.(2013).Synthesis of Pinacol Arylboronates from Aromatic Amines: A Metal-Free Transformation.JOURNAL OF ORGANIC CHEMISTRY,78(5),1923-1933.
MLA	Qiu, Di,et al."Synthesis of Pinacol Arylboronates from Aromatic Amines: A Metal-Free Transformation".JOURNAL OF ORGANIC CHEMISTRY 78.5(2013):1923-1933.