Photoactive Oligo(p-phenylenevinylene) Functionalized with Phospholipid Units for Control and Visualization of Delivery into Living Cells

doi:10.1021/acsami.8b07847

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	Photoactive Oligo(p-phenylenevinylene) Functionalized with Phospholipid Units for Control and Visualization of Delivery into Living Cells
	Chen, Yanyan 1,2; Zhou, Lingyun 1,2; Wang, Jianwu 1,2; Liu, Xiaoyan 3; Lu, Huan 1; Liu, Libing 1,2; Lv, Fengting 1; Wang, Shu 1,2
刊名	ACS APPLIED MATERIALS & INTERFACES
	2018-08-22
卷号	10 期号:33 页码:27555-27561
关键词	Conjugated Molecular Materials Oligo(P-phenylenevinylene) Derivative Phospholipid Controllable Delivery Fluorescent Imaging
ISSN号	1944-8244
DOI	10.1021/acsami.8b07847
英文摘要	To take advantage of the excellent optical properties of conjugated polymers (CPs) or conjugated oligomers (COs) for biological applications, there is still a requirement to find new ways to deliver these conjugated molecular materials into cells in a facile, controllable, and noninvasive manner. Herein, a photoactive oligo(p-phenylenevinylene) (OPV) derivative was covalently attached with phospholipid units (OPV-lipid) to enhance its dispersion in water and facilitate its internalization by cells. OPV-lipid could be delivered into either the cell membrane or cytoplasm controllably through the assistance of liposomes with different formulas. It could also act as a fluorescent probe for cell imaging and visualization of the delivery process. This work shows a good potential for delivering functional conjugated molecular materials into cells in a controllable way.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000442706600002
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/42377]
专题	中国科学院化学研究所
通讯作者	Liu, Libing; Wang, Shu
作者单位	1.Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Coll Chem, Beijing 100049, Peoples R China 3.Shandong Univ, Sch Phys, Jinan 250100, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Chen, Yanyan,Zhou, Lingyun,Wang, Jianwu,et al. Photoactive Oligo(p-phenylenevinylene) Functionalized with Phospholipid Units for Control and Visualization of Delivery into Living Cells[J]. ACS APPLIED MATERIALS & INTERFACES,2018,10(33):27555-27561.
APA	Chen, Yanyan.,Zhou, Lingyun.,Wang, Jianwu.,Liu, Xiaoyan.,Lu, Huan.,...&Wang, Shu.(2018).Photoactive Oligo(p-phenylenevinylene) Functionalized with Phospholipid Units for Control and Visualization of Delivery into Living Cells.ACS APPLIED MATERIALS & INTERFACES,10(33),27555-27561.
MLA	Chen, Yanyan,et al."Photoactive Oligo(p-phenylenevinylene) Functionalized with Phospholipid Units for Control and Visualization of Delivery into Living Cells".ACS APPLIED MATERIALS & INTERFACES 10.33(2018):27555-27561.