Antioxidative extracts and phenols isolated from Qinghai-Tibet Plateau medicinal plant Saxifraga tangutica Engl.

	Antioxidative extracts and phenols isolated from Qinghai-Tibet Plateau medicinal plant Saxifraga tangutica Engl.
	Dang, Jun ; Tao, Yanduo ; Shao, Yun ; Mei, Lijuan ; Zhang, Li ; Wang, Qilan
刊名	INDUSTRIAL CROPS AND PRODUCTS
	2015-12-30
英文摘要	Saxifraga tangutica Engl., is a medicinal herb that grows on the Qinghai-Tibet Plateau. Extracts and phenols fromthe Qinghai population have been subjected to antioxidative assays against DPPH radical-scavenging and reducing power (FRAP). The 50% ethanol extract showed strong antioxidative activity against DPPH and FRAP, with IC50 +/- SEM [mu g/mL] values of 9.38 +/- 0.46 and 15.46 +/- 0.52, respectively. The antioxidative activity-guided fractionations were performed according to the DPPH and FRAP screening results. Fourteen fractions from the 50% ethanol extract showed dissimilar antioxidative activity against DPPH and FRAP of 8.16 +/- 0.76 similar to 38.42 +/- 0.58 mu g/mL and 13.22 +/- 0.68 similar to 61.47 +/- 0.49 mu g/mL. The chemical assayguided separation of the active fractions (fractions 3, 6, 7 and 8) led to eight phenols: protocatechuic aldehyde (1), ethyl gallate (2), rhododendrin (3), p-hydroxyacetophenone (4), rhododendrol (5), protocatechuic acid ethyl ester (6), frambinone (7) and ethylparaben (8). All phenols are reported here for the first time from S. tangutica Engl. Protocatechuic aldehyde (1), ethyl gallate (2), rhododendrin (3) and protocatechuic acid ethyl ester (6) showed strong antioxidative activities (IC50 +/- SEM [mM] between 8.79 +/- 0.15 and 4.25 +/- 0.47 and between 6.15 +/- 0.48 and 2.83 +/- 0.49) against DPPH and FRAP. (C) 2015 Elsevier B.V. All rights reserved.
内容类型	期刊论文
源URL	[http://210.75.249.4/handle/363003/6512]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Dang, Jun,Tao, Yanduo,Shao, Yun,et al. Antioxidative extracts and phenols isolated from Qinghai-Tibet Plateau medicinal plant Saxifraga tangutica Engl.[J]. INDUSTRIAL CROPS AND PRODUCTS,2015.
APA	Dang, Jun,Tao, Yanduo,Shao, Yun,Mei, Lijuan,Zhang, Li,&Wang, Qilan.(2015).Antioxidative extracts and phenols isolated from Qinghai-Tibet Plateau medicinal plant Saxifraga tangutica Engl..INDUSTRIAL CROPS AND PRODUCTS.
MLA	Dang, Jun,et al."Antioxidative extracts and phenols isolated from Qinghai-Tibet Plateau medicinal plant Saxifraga tangutica Engl.".INDUSTRIAL CROPS AND PRODUCTS (2015).