Chemical constituents investigation of Daphne tangutica

	Chemical constituents investigation of Daphne tangutica
	Zhou, Yan 1; Pan, Li 1,2; Zhang, Xiao Feng 2; Deng, Ye 3; Wang, Huan 2; Ding, Li Sheng 1
刊名	FITOTERAPIA
	2010
卷号	81 期号:1 页码:38-41
关键词	Daphne Tangutica Thymelaeaceae Daphnane Diterpene Lignan Coumarine Phenylpropanoid Derivative
ISSN号	0367-326X
文献子类	Article
英文摘要	A phytochemical study of an ethanol-soluble extract from the root barks of Daphne tangutica Maxim., a traditional Tibetan herb medicine, led to the isolation of 30 compounds, including eight daphnane diterpenes, nine coumarines, six lignans, five phenylpropanoid derivatives, beta-sitosterol and p-hydroxy benzonate. Two compounds out of these isolates are new daphne diterpene analogs, and their structures were established as 1,2 alpha-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy- resiniferomol-14-benzonate, and 1,2 beta-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy-resiniferonol-14-benzonate, respectively, on the basis of spectroscopic methods. Additionally, this is the first time that 13 known compounds have been isolated and identified from this traditional Tibetan medicinal plant. (C) 2009 Published by Elsevier B.V.; A phytochemical study of an ethanol-soluble extract from the root barks of Daphne tangutica Maxim., a traditional Tibetan herb medicine, led to the isolation of 30 compounds, including eight daphnane diterpenes, nine coumarines, six lignans, five phenylpropanoid derivatives, beta-sitosterol and p-hydroxy benzonate. Two compounds out of these isolates are new daphne diterpene analogs, and their structures were established as 1,2 alpha-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy- resiniferomol-14-benzonate, and 1,2 beta-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy-resiniferonol-14-benzonate, respectively, on the basis of spectroscopic methods. Additionally, this is the first time that 13 known compounds have been isolated and identified from this traditional Tibetan medicinal plant. (C) 2009 Published by Elsevier B.V.
WOS关键词	DITERPENES ; GLYCOSIDES
WOS研究方向	Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000273967500008
公开日期	2011-12-13
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn//handle/363003/1758]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China 2.Chinese Acad Sci, NW Plateau Inst Biol, Xining 810001, Peoples R China 3.Ohio State Univ, Coll Pharm, Div Med Chem & Pharmacognosy, Columbus, OH 43210 USA
推荐引用方式 GB/T 7714	Zhou, Yan,Pan, Li,Zhang, Xiao Feng,et al. Chemical constituents investigation of Daphne tangutica[J]. FITOTERAPIA,2010,81(1):38-41.
APA	Zhou, Yan,Pan, Li,Zhang, Xiao Feng,Deng, Ye,Wang, Huan,&Ding, Li Sheng.(2010).Chemical constituents investigation of Daphne tangutica.FITOTERAPIA,81(1),38-41.
MLA	Zhou, Yan,et al."Chemical constituents investigation of Daphne tangutica".FITOTERAPIA 81.1(2010):38-41.