Spatial and temporal distribution of antibiotic resistomes in a peri-urban area is associated significantly with anthropogenic activities

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 城市与区域生态国家重点实验室

	Spatial and temporal distribution of antibiotic resistomes in a peri-urban area is associated significantly with anthropogenic activities
	Xiang, Qian; Chen, Qing-Lin; Zhu, Dong; An, Xin-Li; Yang, Xiao-Ru; Su, Jian-Qiang; Qiao, Min; Zhu, Yong-Guan
刊名	ENVIRONMENTAL POLLUTION
	2018-04-01
卷号	235 页码:525-533
关键词	Antibiotic resistance Urbanization Spatio-temporal Watershed
ISSN号	0269-7491
文献子类	Article
英文摘要	With the rapid development of urbanization and industrialization, the peri-urban areas are often the sites for waste dumps, which may exacerbate the occurrence and spread of antibiotic resistance from waste to soil bacteria. However, the profiles of antibiotic resistomes and the associated factors influencing their dissemination in peri-urban areas have not been fully explored. Here, we characterized the antibiotic resistance genes (ARGs) in peri-urban arable and pristine soils in four seasons at the watershed scale, by using high-throughput qPCR. ARGs in peri-urban soils were diverse and abundant, with a total of 222 genes were detected in the peri-urban soil samples. The arable soil harbored more diverse ARGs compared to the pristine soils, and nearly all the ARGs detected in the pristine soils were also detected in the farmlands. A random forest prediction showed that the overall patterns of ARGs clustered closely with the landuse type. Mantel test and partial redundancy analysis indicated that bacterial community variation is a major contributor to antibiotic resistome alteration. Significant positive correlation was found between the abundance of ARGs and mobile genetic elements (MGEs), suggesting potential mobility of ARGs in peri-urban areas. Our results extend knowledge of the resistomes compositions in peri-urban areas, and suggest that anthropogenic activities driving its spatial and temporal distribution. (C) 2018 Elsevier Ltd. All rights reserved.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/40663]
专题	生态环境研究中心_城市与区域生态国家重点实验室
推荐引用方式 GB/T 7714	Xiang, Qian,Chen, Qing-Lin,Zhu, Dong,et al. Spatial and temporal distribution of antibiotic resistomes in a peri-urban area is associated significantly with anthropogenic activities[J]. ENVIRONMENTAL POLLUTION,2018,235:525-533.
APA	Xiang, Qian.,Chen, Qing-Lin.,Zhu, Dong.,An, Xin-Li.,Yang, Xiao-Ru.,...&Zhu, Yong-Guan.(2018).Spatial and temporal distribution of antibiotic resistomes in a peri-urban area is associated significantly with anthropogenic activities.ENVIRONMENTAL POLLUTION,235,525-533.
MLA	Xiang, Qian,et al."Spatial and temporal distribution of antibiotic resistomes in a peri-urban area is associated significantly with anthropogenic activities".ENVIRONMENTAL POLLUTION 235(2018):525-533.