The interaction between positive schizotypy and high sensitivity C-reactive protein on response inhibition in female individuals | |
Gong Jingbo1; Wang Ya2; Liu Jianbo3; Fu Xiaogao1; Cheung, Eric F. C.4; Chan, Raymond C. K.2,5 | |
刊名 | PSYCHIATRY RESEARCH |
2019-04-01 | |
卷号 | 274页码:365-371 |
关键词 | Schizotypy Childhood maltreatment High sensitive C-reactive protein Response inhibition |
ISSN号 | 0165-1781 |
DOI | 10.1016/j.psychres.2019.02.064 |
产权排序 | 2 |
文献子类 | article |
英文摘要 | This study aimed to measure the associations between high sensitivity C-reactive protein (hsCRP), childhood maltreatment (CM), schizotypy and response inhibition, and to explore the interactions between hsCRP, CM and schizotypy on response inhibition. Two hundred and fourteen participants completed the Stop-Signal Task (SST), the Schizotypy Personality Questionnaire (SPQ) and the Childhood Trauma Questionnaire-Short Form (CTQ), which measured response inhibition, schizotypy and history of CM respectively. The level of hsCRP was also measured. The high schizotypy group (n = 114) had higher scores on SPQ and CTQ, higher hsCRP levels and longer SST reaction times (SSRTs) than the low schizotypy group (n = 100). In female participants, SSRT had a positive correlation with the SPQ positive factor and the disorganized SPQ factor and a positive correlation with physical neglect. HsCRP was positively correlated with the SPQ negative factor and positive SPQ factor. In male participants, SSRT was negatively correlated with emotional neglect and physical neglect. The majority of correlations between CTQ and SPQ variables were significant in both female and male participants. In female participants, hsCRP significantly predicted SSRT, and hsCRP significantly interacted with positive schizotypy in predicting SSRT. |
资助项目 | China Postdoctoral Science Foundation[2016M591278] ; Hunan Natural Science Foundation[2017JJ3240] ; Hunan Education Department Excellent Youth Fund[16B201] ; National Key Research and Development Programme[2016YFC0906402] ; Beijing Municipal Science & Technology Commission[Z161100000216138] ; CAS Key Laboratory of Mental Health, the Institute of Psychology |
WOS关键词 | CELLULAR IMMUNE-RESPONSES ; FORMAL THOUGHT-DISORDER ; CHILDHOOD SEXUAL-ABUSE ; BODY-MASS INDEX ; COGNITIVE IMPAIRMENT ; SCHIZOPHRENIA-PATIENTS ; INFLAMMATORY MARKERS ; LATENT INHIBITION ; WORKING-MEMORY ; TRAUMA |
WOS研究方向 | Psychiatry |
语种 | 英语 |
出版者 | ELSEVIER IRELAND LTD |
WOS记录号 | WOS:000465059300048 |
资助机构 | China Postdoctoral Science Foundation ; Hunan Natural Science Foundation ; Hunan Education Department Excellent Youth Fund ; National Key Research and Development Programme ; Beijing Municipal Science & Technology Commission ; CAS Key Laboratory of Mental Health, the Institute of Psychology |
内容类型 | 期刊论文 |
源URL | [http://ir.psych.ac.cn/handle/311026/28949] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Chan, Raymond C. K. |
作者单位 | 1.Hunan Univ Chinese Med, Dept Appl Psychol, Changsha 410208, Hunan, Peoples R China 2.Chinese Acad Sci, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, Inst Psychol, Beijing, Peoples R China 3.Cent S Univ, Mental Hlth Inst, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China 4.Castle Peak Hosp, Hong Kong, Peoples R China 5.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Gong Jingbo,Wang Ya,Liu Jianbo,et al. The interaction between positive schizotypy and high sensitivity C-reactive protein on response inhibition in female individuals[J]. PSYCHIATRY RESEARCH,2019,274:365-371. |
APA | Gong Jingbo,Wang Ya,Liu Jianbo,Fu Xiaogao,Cheung, Eric F. C.,&Chan, Raymond C. K..(2019).The interaction between positive schizotypy and high sensitivity C-reactive protein on response inhibition in female individuals.PSYCHIATRY RESEARCH,274,365-371. |
MLA | Gong Jingbo,et al."The interaction between positive schizotypy and high sensitivity C-reactive protein on response inhibition in female individuals".PSYCHIATRY RESEARCH 274(2019):365-371. |
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