Post-synthetic modification of an amino-functionalized metal-organic framework for highly efficient enrichment of N-linked glycopeptides

doi:10.1039/c6nr02490d

	Post-synthetic modification of an amino-functionalized metal-organic framework for highly efficient enrichment of N-linked glycopeptides
	Sun, Yunlong 2; Bai, Yu 1; Liu, Huwei 1; Xu, Linnan 1; Li, Ze 1; Ma, Wen 1
刊名	NANOSCALE
	2016
卷号	8 期号:21 页码:10908-10912
ISSN号	2040-3364
DOI	10.1039/c6nr02490d
文献子类	Article
英文摘要	A maltose-functionalized metal-organic framework (MOF), MIL-101(Cr)-maltose, was developed via a simple two step post-synthetic modification of MIL-101(Cr)-NH2. With the use of this nanomaterial, 33 glycopeptides were detected from the digest of human immunoglobulin G, demonstrating its high efficiency in glycoproteomic analysis. More importantly, the generic functionalization route from amino-derived MOFs opens a new perspective in material design in sample preparation.
WOS关键词	CHROMATOGRAPHIC-SEPARATION ; SELECTIVE ENRICHMENT ; MASS-SPECTROMETRY ; MAGNETIC NANOPARTICLES ; GLYCOPROTEINS ; GLYCOSYLATION ; MIL-101(CR) ; ADSORPTION ; CHEMISTRY ; CAPTURE
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000380888200006
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/170016]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者	Bai, Yu
作者单位	1.Peking Univ, Coll Chem & Mol Engn, Key Lab Bioorgan Chem & Mol Engn, Beijing Natl Lab Mol Sci,Minist Educ, Beijing 100871, Peoples R China 2.Peking Univ, Ctr Soft Matter Sci & Engn, Beijing 100871, Peoples R China
推荐引用方式 GB/T 7714	Sun, Yunlong,Bai, Yu,Liu, Huwei,et al. Post-synthetic modification of an amino-functionalized metal-organic framework for highly efficient enrichment of N-linked glycopeptides[J]. NANOSCALE,2016,8(21):10908-10912.
APA	Sun, Yunlong,Bai, Yu,Liu, Huwei,Xu, Linnan,Li, Ze,&Ma, Wen.(2016).Post-synthetic modification of an amino-functionalized metal-organic framework for highly efficient enrichment of N-linked glycopeptides.NANOSCALE,8(21),10908-10912.
MLA	Sun, Yunlong,et al."Post-synthetic modification of an amino-functionalized metal-organic framework for highly efficient enrichment of N-linked glycopeptides".NANOSCALE 8.21(2016):10908-10912.