Chiral sensors for determining the absolute configurations of -amino acid derivatives | |
Fan, Hongjun2; Chen, Zhongxiang1,3; Yang, Shiwei1,3; Bian, Guangling1,3; Song, Ling1,3 | |
刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
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2018-10-07 | |
卷号 | 16期号:37页码:6933-6939 |
ISSN号 | 1477-0520 |
DOI | 10.1039/c8ob01933a |
通讯作者 | Bian, Guangling(glb@fjirsm.ac.cn) ; Song, Ling(songling@fjirsm.ac.cn) |
英文摘要 | A simple strategy for configurational assignments of alpha-amino acids has been developed by comparison of the proton NMR chemical shift values of the alpha hydrogens of N-phthaloyl protected alpha-amino acids in the presence of (R)-CSA 1 and (S)-CSA 1, respectively. Highly resolved NMR spectra can be obtained directly on the mixed solution of the chiral solvating agents with N-phthaloyl protected alpha-amino acids in NMR tubes, giving well distinguishable proton signals without interference which dramatically improve the accuracy of assignment and hasten the assigning procedure. The strategy is widely applicable for varied natural and non-natural amino acids. |
资助项目 | Strategic Priority Research Program of the Chinese Academy of Sciences[XDB20000000] ; DICP[DICP DMTO201404] ; Natural Science Foundation of Fujian Province, China[2018J01029] ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences |
WOS关键词 | ALPHA-HYDROXY ACIDS ; NMR-SPECTROSCOPY ; CARBOXYLIC-ACIDS ; SOLVATING AGENTS ; ENANTIOSELECTIVE RECOGNITION ; H-1-NMR SPECTROSCOPY ; C(SP(3))-H BONDS ; SHIFT-REAGENT ; F-19 NMR ; DISCRIMINATION |
WOS研究方向 | Chemistry |
语种 | 英语 |
出版者 | ROYAL SOC CHEMISTRY |
WOS记录号 | WOS:000445637600014 |
资助机构 | Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; DICP ; DICP ; Natural Science Foundation of Fujian Province, China ; Natural Science Foundation of Fujian Province, China ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; DICP ; DICP ; Natural Science Foundation of Fujian Province, China ; Natural Science Foundation of Fujian Province, China ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; DICP ; DICP ; Natural Science Foundation of Fujian Province, China ; Natural Science Foundation of Fujian Province, China ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; DICP ; DICP ; Natural Science Foundation of Fujian Province, China ; Natural Science Foundation of Fujian Province, China ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences |
内容类型 | 期刊论文 |
源URL | [http://cas-ir.dicp.ac.cn/handle/321008/166986] ![]() |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
通讯作者 | Bian, Guangling; Song, Ling |
作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China 3.Chinese Acad Sci, Fujian Inst Res Struct Matter, Key Lab Coal Ethylene Glycol & its Related Techno, Fuzhou 350002, Fujian, Peoples R China |
推荐引用方式 GB/T 7714 | Fan, Hongjun,Chen, Zhongxiang,Yang, Shiwei,et al. Chiral sensors for determining the absolute configurations of -amino acid derivatives[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2018,16(37):6933-6939. |
APA | Fan, Hongjun,Chen, Zhongxiang,Yang, Shiwei,Bian, Guangling,&Song, Ling.(2018).Chiral sensors for determining the absolute configurations of -amino acid derivatives.ORGANIC & BIOMOLECULAR CHEMISTRY,16(37),6933-6939. |
MLA | Fan, Hongjun,et al."Chiral sensors for determining the absolute configurations of -amino acid derivatives".ORGANIC & BIOMOLECULAR CHEMISTRY 16.37(2018):6933-6939. |
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