An organic-base catalyzed asymmetric 1,4-addition of tritylthiol to in situ generated aza-o-quinone methides at the H2O/DCM interface | |
Liu, Yan1; Li, Can1; Liu, Xianghui1,2; Wang, Kai1,2; Guo, Wengang1 | |
刊名 | CHEMICAL COMMUNICATIONS |
2019-03-04 | |
卷号 | 55期号:18页码:2668-2671 |
ISSN号 | 1359-7345 |
DOI | 10.1039/c8cc09382b |
通讯作者 | Liu, Yan(yanliu503@dicp.ac.cn) ; Li, Can(canli@dicp.ac.cn) |
英文摘要 | Based on an efficient method for in situ generation of N-o-QM species in the presence of a base, enantioselective catalytic conjugated additions of tritylthiol to in situ generated N-o-QMs are reported. Acid-base bifunctional organocatalyst 4c (10 mol%) enables these transformations with high stereoselectivities (up to 94% ee) using H2O/DCM as a solvent under mild conditions. |
资助项目 | National Natural Science Foundation of China[21871254] ; National Natural Science Foundation of China[21532006] ; National Natural Science Foundation of China[21472187] ; DICP[DICP ZZBS201602] |
WOS关键词 | ENANTIOSELECTIVE 4+2 CYCLOADDITION ; HYDROXYBENZYL ALCOHOLS ; ORTHO-XYLYLENES ; ACID CATALYSIS ; ROUTE ; TRIARYLMETHANES ; ANNULATION ; ENAMIDES ; INDOLES ; ACCESS |
WOS研究方向 | Chemistry |
语种 | 英语 |
出版者 | ROYAL SOC CHEMISTRY |
WOS记录号 | WOS:000459737100017 |
资助机构 | National Natural Science Foundation of China ; National Natural Science Foundation of China ; DICP ; DICP ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; DICP ; DICP ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; DICP ; DICP ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; DICP ; DICP |
内容类型 | 期刊论文 |
源URL | [http://cas-ir.dicp.ac.cn/handle/321008/166036] |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
通讯作者 | Liu, Yan; Li, Can |
作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Liu, Yan,Li, Can,Liu, Xianghui,et al. An organic-base catalyzed asymmetric 1,4-addition of tritylthiol to in situ generated aza-o-quinone methides at the H2O/DCM interface[J]. CHEMICAL COMMUNICATIONS,2019,55(18):2668-2671. |
APA | Liu, Yan,Li, Can,Liu, Xianghui,Wang, Kai,&Guo, Wengang.(2019).An organic-base catalyzed asymmetric 1,4-addition of tritylthiol to in situ generated aza-o-quinone methides at the H2O/DCM interface.CHEMICAL COMMUNICATIONS,55(18),2668-2671. |
MLA | Liu, Yan,et al."An organic-base catalyzed asymmetric 1,4-addition of tritylthiol to in situ generated aza-o-quinone methides at the H2O/DCM interface".CHEMICAL COMMUNICATIONS 55.18(2019):2668-2671. |
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