Characterization and identification of chemical components in Neopicrorhiza scrphulariiflora roots by liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry

	Characterization and identification of chemical components in Neopicrorhiza scrphulariiflora roots by liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry
	Li, Chunting ; Liu, Yongqiang ; Abdulla, Rahima ; Aisa, Haji Akber ; Suo, Yourui
刊名	ANALYTICAL METHODS ; Li, CT; Liu, YQ; Abdulla, R; Aisa, HA; Suo, YR.Characterization and identification of chemical components in Neopicrorhiza scrphulariiflora roots by liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry,ANALYTICAL METHODS,2014,6(11):3634
	2014-06-07
英文摘要	Liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry (LC-ESI-QTOF-MS) was applied to identify chemical components occurring in Neopicrorhiza scrphulariiflora roots. 24 compounds, including 12 iridoid glycosides, 3 phenyl glycosides and 9 phenylethanoid glycosides, were detected and tentatively characterized according to accurate mass measurements and their characteristic fragmentation at low and high collision energy. Meanwhile, appropriate fragmentation pathways were proposed based on definite composition of the product ions. 6'-O-Feruloyl-3,4-dihydrocatalpol and 1-[2-(4-(3,4-dihydroxycinnamoyl)-3-glucosyl)glucosy]ethy-3-hydroxy-4-methoxybenzene are potentially novel compounds. 6'-O-Caffeoylcatalpol and maxoside were characterized in N. scrphulariiflora for the first time. This study established that the LC-ESI-QTOF-MS method is efficient for identifying, and could be the basis for the comprehensive quality control of, N. scrphulariiflora roots.; Liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry (LC-ESI-QTOF-MS) was applied to identify chemical components occurring in Neopicrorhiza scrphulariiflora roots. 24 compounds, including 12 iridoid glycosides, 3 phenyl glycosides and 9 phenylethanoid glycosides, were detected and tentatively characterized according to accurate mass measurements and their characteristic fragmentation at low and high collision energy. Meanwhile, appropriate fragmentation pathways were proposed based on definite composition of the product ions. 6'-O-Feruloyl-3,4-dihydrocatalpol and 1-[2-(4-(3,4-dihydroxycinnamoyl)-3-glucosyl)glucosy]ethy-3-hydroxy-4-methoxybenzene are potentially novel compounds. 6'-O-Caffeoylcatalpol and maxoside were characterized in N. scrphulariiflora for the first time. This study established that the LC-ESI-QTOF-MS method is efficient for identifying, and could be the basis for the comprehensive quality control of, N. scrphulariiflora roots.
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/4221]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Li, Chunting,Liu, Yongqiang,Abdulla, Rahima,et al. Characterization and identification of chemical components in Neopicrorhiza scrphulariiflora roots by liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry[J]. ANALYTICAL METHODS, Li, CT; Liu, YQ; Abdulla, R; Aisa, HA; Suo, YR.Characterization and identification of chemical components in Neopicrorhiza scrphulariiflora roots by liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry,ANALYTICAL METHODS,2014,6(11):3634,2014.
APA	Li, Chunting,Liu, Yongqiang,Abdulla, Rahima,Aisa, Haji Akber,&Suo, Yourui.(2014).Characterization and identification of chemical components in Neopicrorhiza scrphulariiflora roots by liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry.ANALYTICAL METHODS.
MLA	Li, Chunting,et al."Characterization and identification of chemical components in Neopicrorhiza scrphulariiflora roots by liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry".ANALYTICAL METHODS (2014).