Triterpenoids of Chrysosplenium carnosum | |
Lu, Meng-ya ; Liao, Zhi-xin ; Ji, Lan-ju ; Sun, Hong-fa | |
刊名 | FITOTERAPIA |
2013-03-01 | |
英文摘要 | A phytochemical study of the ethanolic extract of Chrysosplenium carnosum Hook. f. et Thoms. led to the isolation of two new oleanane-type triterpenoids, 6 beta-hydroxy-3-oxoolean-12-en-27-oic acid (1) and 3 beta, 21 alpha-dihydroxyolean-12-en-27-oic acid (2), along with fourteen known compounds (3-16), all of which were isolated from this plant for the first time. The structures of these compounds were established on the basis of spectroscopic methods. Compounds 1-4 were evaluated for their in vitro anti-tumor activities on B16F10, SP2/0 and Hep-G2 cells lines. Compounds 1,3 and 4 exhibited strong inhibitory activity against B16F10 and SP2/0 cells' growth, compared with moderate cytotoxic activity against Hep-G2 cells. However, compound 2 showed to be inactive against these tumor cells. (C) 2013 Elsevier B.V. All rights reserved. |
出版者 | ELSEVIER SCIENCE BV |
内容类型 | 期刊论文 |
源URL | [http://ir.nwipb.ac.cn/handle/363003/6681] |
专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
推荐引用方式 GB/T 7714 | Lu, Meng-ya,Liao, Zhi-xin,Ji, Lan-ju,et al. Triterpenoids of Chrysosplenium carnosum[J]. FITOTERAPIA,2013. |
APA | Lu, Meng-ya,Liao, Zhi-xin,Ji, Lan-ju,&Sun, Hong-fa.(2013).Triterpenoids of Chrysosplenium carnosum.FITOTERAPIA. |
MLA | Lu, Meng-ya,et al."Triterpenoids of Chrysosplenium carnosum".FITOTERAPIA (2013). |
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