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Lead distribution in blood and organs of mice exposed to lead by vein injection
Sun, H. W.1; Ma, D. J.1,2,3; Chao, C. Y.2; Liu, S.2; Yuan, Z. B.3
刊名Environmental technology
2009
卷号30期号:10页码:1051-1057
关键词Lead Vein injection Mice Distribution Flame atomic absorption spectrometry
ISSN号0959-3330
DOI10.1080/09593330903055643
通讯作者Ma, d. j.(madj@ncist.edu.cn)
英文摘要To study lead (pb) distribution in organs and blood in the case of pb poisoning, mice were firstly exposed to pb as 0.1 ml or 0.2 ml of lead nitrate solution (0.1 mg/ml) by vein injection every other day. then, after metabolic absorption, the pb level in the blood and organs of the mice was measured using flame atomic absorption spectrometry. the resulting data showed that 93% of pb in blood wass accumulated in red cells, but this percentage slightly decreased with increasing exposure time and injection volume. for other target organs, the highest pb level was in the kidney, followed by the liver, spleen, heart and lung, and was lowest in the brain. moreover, the pb level in the heart and brain is in a growth trend at all times for 0.1 ml and 0.2 ml of pb injection exposure in 15 days, while the growth trend of pb in other target organs become slow for 0.2 ml of injection after exposure pb 11 days.
WOS关键词LIPID-PEROXIDATION ; BINDING PROTEINS ; CHILDREN ; CADMIUM ; ERYTHROCYTES ; ANAEMIA ; WORKERS ; LEVEL
WOS研究方向Environmental Sciences & Ecology
WOS类目Environmental Sciences
语种英语
出版者TAYLOR & FRANCIS LTD
WOS记录号WOS:000269585200009
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2402700
专题中国科学院大学
通讯作者Ma, D. J.
作者单位1.Hebei Univ, Coll Chem & Environm, Baoding 071002, Peoples R China
2.N China Inst Sci & Technol, Dept Environm, Beijing 101601, Peoples R China
3.Chinese Acad Sci, Grad Univ, Coll Chem & Chem Engn, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Sun, H. W.,Ma, D. J.,Chao, C. Y.,et al. Lead distribution in blood and organs of mice exposed to lead by vein injection[J]. Environmental technology,2009,30(10):1051-1057.
APA Sun, H. W.,Ma, D. J.,Chao, C. Y.,Liu, S.,&Yuan, Z. B..(2009).Lead distribution in blood and organs of mice exposed to lead by vein injection.Environmental technology,30(10),1051-1057.
MLA Sun, H. W.,et al."Lead distribution in blood and organs of mice exposed to lead by vein injection".Environmental technology 30.10(2009):1051-1057.
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