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Regulatory mechanism of spindle movements during oocyte meiotic division
Ai, Jun-Shu1,2; Li, Mo1,2; Schatten, Heide3; Sun, Qing-Yuan1
刊名Asian-australasian journal of animal sciences
2009-11-01
卷号22期号:11页码:1477-1486
关键词Spindle movement Meiotic division Cytoskeleton Oocyte
ISSN号1011-2367
通讯作者Sun, qing-yuan(sunqy@ioz.ac.cn)
英文摘要Female germ cell meiotic divisions arc typically asymmetric, giving rise to two daughter cells with different sizes. spindle movements including spindle migration from the oocyte center to the cortex and spindle rotation from parallel to perpendicular (typically in the mouse) at the cortex are crucial for these asymmetric divisions and therefore are crucial for gamete production. different regulatory mechanisms for spindle movements have been determined in different species and a wide variety of different molecular components and processes that are involved in spindle movements have also been identified in different species. here. we review the current state of knowledge as well as our understanding of mechanisms for spindle movements in different systems with focus on three main aspects: microtubules (mt), microfilaments (mf) and molecules associated with cytoskeletal organization as well as molecules that are not directly related to the cytoskeleton. how they might interact or function independently during female meiotic divisions in different species is discussed in detail.
WOS关键词POLAR BODY FORMATION ; CAENORHABDITIS-ELEGANS EMBRYOS ; ASYMMETRIC CELL-DIVISION ; MAMMALIAN EGG ACTIVATION ; MOUSE OOCYTES ; ARP2/3 COMPLEX ; FISSION YEAST ; MICROTUBULE ORGANIZATION ; PROTEIN-KINASE ; MOLECULAR-MECHANISMS
WOS研究方向Agriculture
WOS类目Agriculture, Dairy & Animal Science
语种英语
出版者ASIAN-AUSTRALASIAN ASSOC ANIMAL PRODUCTION SOC
WOS记录号WOS:000271726500003
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2399404
专题中国科学院大学
通讯作者Sun, Qing-Yuan
作者单位1.Chinese Acad Sci, Inst Zool, State Key Lab Reprod Biol, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100080, Peoples R China
3.Univ Missouri, Dept Vet Pathobiol, Columbia, MO 65211 USA
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GB/T 7714
Ai, Jun-Shu,Li, Mo,Schatten, Heide,et al. Regulatory mechanism of spindle movements during oocyte meiotic division[J]. Asian-australasian journal of animal sciences,2009,22(11):1477-1486.
APA Ai, Jun-Shu,Li, Mo,Schatten, Heide,&Sun, Qing-Yuan.(2009).Regulatory mechanism of spindle movements during oocyte meiotic division.Asian-australasian journal of animal sciences,22(11),1477-1486.
MLA Ai, Jun-Shu,et al."Regulatory mechanism of spindle movements during oocyte meiotic division".Asian-australasian journal of animal sciences 22.11(2009):1477-1486.
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