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	Acylated iridoids with cytotoxicity from valeriana jatamansi
	Lin, Sheng1; Shen, Yun-Heng1; Li, Hui-Liang1; Yang, Xian-Wen1; Chen, Tao3,4; Lu, Long-Hai1; Huang, Zheng-Sheng1; Liu, Run-Hui1; Xu, Xi-Ke1; Zhang, Wei-Dong1,2
刊名	Journal of natural products
	2009-04-01
卷号	72期号:4页码:650-655
ISSN号	0163-3864
DOI	10.1021/np800716f
通讯作者	Zhang, wei-dong(wdzhangy@hotmail.com)
英文摘要	Thirteen new acylated iridoids, jatamanvaltrates a-m (1-13), together with nine known valepotriates (14-22), were isolated from the whole plants of valeriana jatamansi (syn. valeriana wallichii). the structures of these new compounds were assigned by detailed interpretation of spectroscopic data. jatamanvaltrates d (4) and h (9) are the first examples of naturally occurring valepotriates containing an o-hydroxybenzoyloxy moiety at c-10. all isolated compounds were tested for their cytotoxicity against lung adenocarcinoma (a549), metastatic prostate cancer (pc-3m), colon cancer (hct-8), and hepatoma (bel7402) cell lines.
WOS关键词	COLORIMETRIC ASSAY ; NATURAL SUBSTANCES ; ACTIVE AGENTS ; VALEPOTRIATE ; OFFICINALIS ; WALLICHII ; ROOTS ; CONFIGURATION ; VALTRATE ; LINARIN
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
WOS类目	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000265530000009
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2396220
专题	中国科学院大学
通讯作者	Zhang, Wei-Dong
作者单位	1.Second Mil Med Univ, Coll Pharm, Dept Phytochem, Shanghai 200433, Peoples R China 2.Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China 3.Chinese Acad Sci, Grad Sch, Shanghai 200031, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci, Key Lab Nutr & Metab, Shanghai 200031, Peoples R China
推荐引用方式 GB/T 7714	Lin, Sheng,Shen, Yun-Heng,Li, Hui-Liang,et al. Acylated iridoids with cytotoxicity from valeriana jatamansi[J]. Journal of natural products,2009,72(4):650-655.
APA	Lin, Sheng.,Shen, Yun-Heng.,Li, Hui-Liang.,Yang, Xian-Wen.,Chen, Tao.,...&Wang, Hui.(2009).Acylated iridoids with cytotoxicity from valeriana jatamansi.Journal of natural products,72(4),650-655.
MLA	Lin, Sheng,et al."Acylated iridoids with cytotoxicity from valeriana jatamansi".Journal of natural products 72.4(2009):650-655.

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