| Characteristics of the lrha subfamily of transcriptional regulators from sinorhizobium meliloti | |
| Qi, Mingsheng1,2; Luo, Li1,2; Cheng, Haiping3; Zhu, Jiabi1; Yu, Guanqiao1 | |
| 刊名 | Acta biochimica et biophysica sinica
 |
| 2008-02-01 | |
| 卷号 | 40期号:2页码:166-173 |
| 关键词 | Lrha subfamily Lysr-type transcriptional regulator Sinorhizobium meliloti |
| ISSN号 | 1672-9145 |
| DOI | 10.1111/j.1745-7270.2008.00378.x |
| 通讯作者 | Yu, guanqiao(gqyu@sippe.ac.cn) |
| 英文摘要 | In our previous work, we identified 94 putative genes encoding lysr-type transcriptional regulators from sinorhizobium meliloti. all of these putative lysr genes were mutagenized using plasmid insertions to determine their phenotypes. six lysr-type regulators, encoded by mutants sma1979, smb20715, smc00820, smc04163, smc03975, and smc04315, showed similar amino acid sequences (30%) and shared the conserved dna-binding domain with lrha, hexa, or dgdr phenotype analysis of these gene mutants indicated that the regulators control the swimming behaviors of the bacteria, production of quorum-sensing signals, and secretion of extracellular proteins. these characteristics are very similar to those of lrha, hexa, and dgdr thus, we refer to this group as the lrha subfamily. sequence analysis showed that a great number of homologous genes of the lrha subfamily were distributed in the alpha, beta, and gamma subdivisions of proteobacteria, and a few in actinobacteria. these findings could provide new clues to the roles of the lysr gene family. |
| WOS关键词 | QUORUM-SENSING SYSTEM ; GENE-EXPRESSION ; VIRULENCE ; MOTILITY ; EXOPOLYSACCHARIDE ; HOMOLOG ; LACTONE ; RPOS ; HEXA |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biophysics |
| WOS类目 | Biochemistry & Molecular Biology ; Biophysics |
| 语种 | 英语 |
| 出版者 | BLACKWELL PUBLISHING |
| WOS记录号 | WOS:000253501900010 |
| 内容类型 | 期刊论文 |
| URI标识 | http://www.corc.org.cn/handle/1471x/2390970 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Yu, Guanqiao |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Plant Physiol & Ecol, Mol Genet Lab, Shanghai 200032, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.CUNY, Lehman Coll, Dept Biol Sci, New York, NY 10468 USA |
| 推荐引用方式 GB/T 7714 | Qi, Mingsheng,Luo, Li,Cheng, Haiping,et al. Characteristics of the lrha subfamily of transcriptional regulators from sinorhizobium meliloti[J]. Acta biochimica et biophysica sinica,2008,40(2):166-173. |
| APA | Qi, Mingsheng,Luo, Li,Cheng, Haiping,Zhu, Jiabi,&Yu, Guanqiao.(2008).Characteristics of the lrha subfamily of transcriptional regulators from sinorhizobium meliloti.Acta biochimica et biophysica sinica,40(2),166-173. |
| MLA | Qi, Mingsheng,et al."Characteristics of the lrha subfamily of transcriptional regulators from sinorhizobium meliloti".Acta biochimica et biophysica sinica 40.2(2008):166-173. |
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