A promising electrochemical biosensing platform based on graphitized ordered mesoporous carbon

	A promising electrochemical biosensing platform based on graphitized ordered mesoporous carbon
	Lu, Xianbo 1; Xiao, Yi 2; Lei, Zhibin 2; Chen, Jiping 1; Zhang, Haijun 1; Ni, Yuwen 1; Zhang, Qing 1
刊名	journal of materials chemistry
	2009
卷号	19 期号:27 页码:4707-4714
通讯作者	陈吉平
产权排序	1;1
英文摘要	three dimensional ordered graphitized mesoporous carbon gmc-6 (pore diameter similar to 6 nm) and gmc-13 (pore diameter similar to 13 nm), prepared by a nickel-catalyzed template-assisted method, were explored systematically for the construction of enzyme-based electrochemical biosensors. comparative studies revealed that gmc-6 offer significant advantages over gmc-13 and graphitized multiwalled carbon nanotubes (cnts) in facilitating the direct electron transfer of entrapped hemoglobin and improving the performance of fabricated biosensors. the possible factors that affect the biosensing performance of these carbon materials were evaluated comprehensively and comparatively based on the characterization of their physical parameters. the biosensor based on gmc-6 displayed excellent analytical performance over a wide linear range along with good stability and selectivity for the detection of hydrogen peroxide. the "entrapment'' immobilization mode and "interspace confinement effect'' (by restraining the unfolding or conformational change of enzyme molecules from inactivation) provided by gmc can result in pore-size-dependent enzymatic stability and bioactivity, which might be a crucial factor for the superior biosensing performance of gmc-6 to that of cnts and gmc-13. graphitized ordered mesoporous carbons with good pore size matching for enzymes proved to be a promising electrochemical biosensing platform.
WOS标题词	science & technology ; physical sciences ; technology
类目[WOS]	chemistry, physical ; materials science, multidisciplinary
研究领域[WOS]	chemistry ; materials science
关键词[WOS]	direct electron-transfer ; hydrogen-peroxide biosensor ; immobilized enzymes ; catalytic activity ; heme-proteins ; hemoglobin ; silica ; electrocatalysis ; construction ; stability
收录类别	SCI
原文出处	false
语种	英语
WOS记录号	WOS:000267571800007
公开日期	2010-11-30
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/102471]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Liaoning Normal Univ, Inst Chem Functionalized Mat, Fac Chem & Chem Engn, Dalian 116029, Peoples R China
推荐引用方式 GB/T 7714	Lu, Xianbo,Xiao, Yi,Lei, Zhibin,et al. A promising electrochemical biosensing platform based on graphitized ordered mesoporous carbon[J]. journal of materials chemistry,2009,19(27):4707-4714.
APA	Lu, Xianbo.,Xiao, Yi.,Lei, Zhibin.,Chen, Jiping.,Zhang, Haijun.,...&Zhang, Qing.(2009).A promising electrochemical biosensing platform based on graphitized ordered mesoporous carbon.journal of materials chemistry,19(27),4707-4714.
MLA	Lu, Xianbo,et al."A promising electrochemical biosensing platform based on graphitized ordered mesoporous carbon".journal of materials chemistry 19.27(2009):4707-4714.