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Highly diastereoselective reactions of 2-lithiated indoles with chiral n-tert-butanesulfinyl aldimines for the synthesis of chiral (2-indolyl) methanamine derivatives
Cheng, Liang; Liu, Li; Sui, Yong; Wang, Dong; Chen, Yong-Jun
刊名Tetrahedron-asymmetry
2007-08-09
卷号18期号:15页码:1833-1843
ISSN号0957-4166
DOI10.1016/j.tetasy.2007.07.029
通讯作者Liu, li(lliu@mail.iccas.ac.cn)
英文摘要Nucleophilic addition reactions of 2-lithiated n-phenylsulfonylindoles with (r)-n-tert-butanesulfinyl aldimines provided chiral (2-indolyl) methanamine derivatives in moderate to good yields (up to 100%) with excellent diastereoselectivities (>99: 1), in which no additional lewis acids were required. (c) 2007 elsevier ltd. all rights reserved.
WOS关键词FRIEDEL-CRAFTS REACTION ; ASYMMETRIC-SYNTHESIS ; SULFINYL IMINES ; ORGANOMETALLIC REAGENTS ; GENERAL-METHOD ; AMINO-ACIDS ; SULFINIMINES ; TRANSFORMATIONS ; 1,2-ADDITIONS ; INDUCTION
WOS研究方向Chemistry
WOS类目Chemistry, Inorganic & Nuclear ; Chemistry, Organic ; Chemistry, Physical
语种英语
出版者PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号WOS:000250063000013
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2380808
专题中国科学院大学
通讯作者Liu, Li
作者单位1.Chinese Acad Sci, Inst Chem, Biol Chem Lab, Beijing Natl Lab Mol Sci, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Cheng, Liang,Liu, Li,Sui, Yong,et al. Highly diastereoselective reactions of 2-lithiated indoles with chiral n-tert-butanesulfinyl aldimines for the synthesis of chiral (2-indolyl) methanamine derivatives[J]. Tetrahedron-asymmetry,2007,18(15):1833-1843.
APA Cheng, Liang,Liu, Li,Sui, Yong,Wang, Dong,&Chen, Yong-Jun.(2007).Highly diastereoselective reactions of 2-lithiated indoles with chiral n-tert-butanesulfinyl aldimines for the synthesis of chiral (2-indolyl) methanamine derivatives.Tetrahedron-asymmetry,18(15),1833-1843.
MLA Cheng, Liang,et al."Highly diastereoselective reactions of 2-lithiated indoles with chiral n-tert-butanesulfinyl aldimines for the synthesis of chiral (2-indolyl) methanamine derivatives".Tetrahedron-asymmetry 18.15(2007):1833-1843.
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