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	The proline-rich domain and the microtubule binding domain of protein tau acting as rna binding domains
	Wang, XingShen; Wang, DongLiang; Zhao, Jing; Qu, MeiHua; Zhou, XiaoHong; He, HaiJin; He, RongQiao
刊名	Protein and peptide letters
	2006
卷号	13期号:7页码:679-685
关键词	Neuronal tau Rna Non-sequence-specific rna-binding Electrostatic interaction Proline rich domain Microtubule binding domain
ISSN号	0929-8665
通讯作者	He, rongqiao(herq@sun5.ibp.ac.cn)
英文摘要	Neuronal tau, through its proline-rich domain and the microtubule binding domain, binds to rna nonsequence-specifically via electrostatic interaction. this binding inhibits the activity of tau. tau and rna were also found to co-localize in sh-sy5y cells suggesting that rna has opportunities to interact with tau in cells.
WOS关键词	PAIRED HELICAL FILAMENTS ; NEUROFIBRILLARY TANGLES ; ALZHEIMERS-DISEASE ; TUBULIN ; BRAIN ; AGGREGATION ; INHIBITION ; POLYANIONS ; EXPRESSION ; ISOFORMS
WOS研究方向	Biochemistry & Molecular Biology
WOS类目	Biochemistry & Molecular Biology
语种	英语
出版者	BENTHAM SCIENCE PUBL LTD
WOS记录号	WOS:000238786500006
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2379680
专题	中国科学院大学
通讯作者	He, RongQiao
作者单位	1.Chinese Acad Sci, Inst Biophys, State Key Lab Brain & Cognit Sci, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Wang, XingShen,Wang, DongLiang,Zhao, Jing,et al. The proline-rich domain and the microtubule binding domain of protein tau acting as rna binding domains[J]. Protein and peptide letters,2006,13(7):679-685.
APA	Wang, XingShen.,Wang, DongLiang.,Zhao, Jing.,Qu, MeiHua.,Zhou, XiaoHong.,...&He, RongQiao.(2006).The proline-rich domain and the microtubule binding domain of protein tau acting as rna binding domains.Protein and peptide letters,13(7),679-685.
MLA	Wang, XingShen,et al."The proline-rich domain and the microtubule binding domain of protein tau acting as rna binding domains".Protein and peptide letters 13.7(2006):679-685.

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