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Controlled drug delivery system based on magnetic hollow spheres/polyelectrolyte multilayer core-shell structure
Zhang, YanQi; Li, LinLin; Tang, Fangqiong; Ren, Jun
刊名Journal of nanoscience and nanotechnology
2006-09-01
卷号6期号:9-10页码:3210-3214
关键词Target drug delivery Magnetic hollow spheres Layer-by-layer Controlled release
ISSN号1533-4880
DOI10.1166/jnn.2006.469
通讯作者Tang, fangqiong()
英文摘要A novel controlled drug delivery system was fabricated by coating chitosan/paa multilayer onto magnetic hollow spheres via a "layer-by-layer" (lbl) assembly approach. cefradine was used as a model drug to evaluate the drug release characteristics of this core-shell hollow structure and the results show that it exhibits a sustained release of the drug and the release rate can be regulated by the ph environment of release medium. it is believed that this core-shell hollow structure, which combines the advantage of controlled delivery as well as magnetic targeting, has commendable potential in drug delivery therapeutics.
WOS关键词POLYELECTROLYTE MICROCAPSULES ; NANOPARTICLES ; SPHERES ; CELLS
WOS研究方向Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS类目Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
语种英语
出版者AMER SCIENTIFIC PUBLISHERS
WOS记录号WOS:000240865900071
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2378669
专题中国科学院大学
通讯作者Tang, Fangqiong
作者单位1.Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100080, Peoples R China
推荐引用方式
GB/T 7714
Zhang, YanQi,Li, LinLin,Tang, Fangqiong,et al. Controlled drug delivery system based on magnetic hollow spheres/polyelectrolyte multilayer core-shell structure[J]. Journal of nanoscience and nanotechnology,2006,6(9-10):3210-3214.
APA Zhang, YanQi,Li, LinLin,Tang, Fangqiong,&Ren, Jun.(2006).Controlled drug delivery system based on magnetic hollow spheres/polyelectrolyte multilayer core-shell structure.Journal of nanoscience and nanotechnology,6(9-10),3210-3214.
MLA Zhang, YanQi,et al."Controlled drug delivery system based on magnetic hollow spheres/polyelectrolyte multilayer core-shell structure".Journal of nanoscience and nanotechnology 6.9-10(2006):3210-3214.
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