The JMJD2 members of histone demethylase revisited | |
Tan, Haidong; Wu, Siguo; Wang, Jinxia; Zhao, Zongbao (Kent) | |
刊名 | molecular biology reports |
2008-12-01 | |
卷号 | 35期号:4页码:551-556 |
关键词 | Eukaryotes Histone demethylation In vivo study JMJD2 Prokaryotes Protein-protein interaction |
通讯作者 | 谭海东 |
产权排序 | 1;1 |
英文摘要 | the study of histone lysine demethylases has become very hot recently. many histone demethylases have been reported by different research groups with various techniques. however, how many histone lysine-methylation states can be removed by one specific demethylase and how many demethylases can remove one specific histone lysine-methylation state? it remains a daunting challenge to answer these questions to date. an in-depth discussion on recent results, three important points were provided: (1) some demethylases can remove more histone lysine-methylation states; (2) some prokaryotes might be endowed with histone lysine demethylases although they are devoid of histones; (3) protein-protein interaction provides a valuable framework for a better understanding of the functions of the histone lysine demethylases. all of these will be beneficial to a better understanding of demethylases and suggest how future research can be improved. |
WOS标题词 | science & technology ; life sciences & biomedicine |
类目[WOS] | biochemistry & molecular biology |
研究领域[WOS] | biochemistry & molecular biology |
关键词[WOS] | androgen-receptor ; functional-characterization ; s-adenosylmethionine ; mammalian-cells ; methyl groups ; h3 ; protein ; family ; lsd1 ; transcription |
收录类别 | SCI |
原文出处 | true |
语种 | 英语 |
WOS记录号 | WOS:000261424100010 |
公开日期 | 2010-11-30 |
内容类型 | 期刊论文 |
源URL | [http://159.226.238.44/handle/321008/101159] |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China |
推荐引用方式 GB/T 7714 | Tan, Haidong,Wu, Siguo,Wang, Jinxia,et al. The JMJD2 members of histone demethylase revisited[J]. molecular biology reports,2008,35(4):551-556. |
APA | Tan, Haidong,Wu, Siguo,Wang, Jinxia,&Zhao, Zongbao .(2008).The JMJD2 members of histone demethylase revisited.molecular biology reports,35(4),551-556. |
MLA | Tan, Haidong,et al."The JMJD2 members of histone demethylase revisited".molecular biology reports 35.4(2008):551-556. |
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