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	Benzothieno[3,2-b]indole derivatives as potent selective estrogen receptor modulators
	Ji, QG; Gao, H; Wang, J; Yang, CC; Hui, X; Yan, XM; Wu, XH; Xie, YY; Wang, MW
刊名	Bioorganic & medicinal chemistry letters
	2005-06-02
卷号	15期号:11页码:2891-2893
关键词	Serm Benzotbieno[3,2-b]indole Estrogen receptor
ISSN号	0960-894X
DOI	10.1016/j.bmel.2005.03.011
通讯作者	Yang, cc()
英文摘要	A series of estrogen receptor ligands based on benzothieno[3,2-b]indole were synthesized and their binding affinity for estrogen receptor subtypes (er alpha and er beta) and effects on mouse uterus and bone were evaluated. some of these compounds showed strong binding affinity to er and significantly increased the bone mineral density of ovariectomized mice. (c) 2005 elsevier ltd. all rights reserved.
WOS关键词	SERMS
WOS研究方向	Pharmacology & Pharmacy ; Chemistry
WOS类目	Chemistry, Medicinal ; Chemistry, Organic
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000229665600039
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2377324
专题	中国科学院大学
通讯作者	Yang, CC
作者单位	1.Chinese Acad Sci, Grad Sch, Shanghai Inst Mat Med, Shanghai Inst Biol Sci,State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Natl Ctr Drug Screening, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Ji, QG,Gao, H,Wang, J,et al. Benzothieno[3,2-b]indole derivatives as potent selective estrogen receptor modulators[J]. Bioorganic & medicinal chemistry letters,2005,15(11):2891-2893.
APA	Ji, QG.,Gao, H.,Wang, J.,Yang, CC.,Hui, X.,...&Wang, MW.(2005).Benzothieno[3,2-b]indole derivatives as potent selective estrogen receptor modulators.Bioorganic & medicinal chemistry letters,15(11),2891-2893.
MLA	Ji, QG,et al."Benzothieno[3,2-b]indole derivatives as potent selective estrogen receptor modulators".Bioorganic & medicinal chemistry letters 15.11(2005):2891-2893.

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