| Nucleocytoplasmic shuttling of influenza a virus proteins | |
| Li, Jing1; Yu, Meng1,2; Zheng, Weinan1; Liu, Wenjun1,2 | |
| 刊名 | Viruses-basel
 |
| 2015-05-01 | |
| 卷号 | 7期号:5页码:2668-2682 |
| ISSN号 | 1999-4915 |
| DOI | 10.3390/v7052668 |
| 通讯作者 | Liu, wenjun(liuwj@im.ac.cn) |
| 英文摘要 | Influenza viruses transcribe and replicate their genomes in the nuclei of infected host cells. the viral ribonucleoprotein (vrnp) complex of influenza virus is the essential genetic unit of the virus. the viral proteins play important roles in multiple processes, including virus structural maintenance, mediating nucleocytoplasmic shuttling of the vrnp complex, virus particle assembly, and budding. nucleocytoplasmic shuttling of viral proteins occurs throughout the entire virus life cycle. this review mainly focuses on matrix protein (m1), nucleoprotein (np), nonstructural protein (ns1), and nuclear export protein (nep), summarizing the mechanisms of their nucleocytoplasmic shuttling and the regulation of virus replication through their phosphorylation to further understand the regulation of nucleocytoplasmic shuttling in host adaptation of the viruses. |
| WOS关键词 | NUCLEAR EXPORT SIGNAL ; RNA-POLYMERASE COMPLEX ; MATRIX PROTEIN ; NS1 PROTEIN ; INTRACELLULAR-LOCALIZATION ; VIRAL RIBONUCLEOPROTEINS ; MESSENGER-RNA ; M1 PROTEIN ; PA SUBUNIT ; NUCLEOPROTEIN |
| WOS研究方向 | Virology |
| WOS类目 | Virology |
| 语种 | 英语 |
| 出版者 | MDPI AG |
| WOS记录号 | WOS:000356228700024 |
| 内容类型 | 期刊论文 |
| URI标识 | http://www.corc.org.cn/handle/1471x/2376722 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Liu, Wenjun |
| 作者单位 | 1.Chinese Acad Sci, Inst Microbiol, Key Lab Pathogen Microbiol & Immunol, Beijing 100101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Jing,Yu, Meng,Zheng, Weinan,et al. Nucleocytoplasmic shuttling of influenza a virus proteins[J]. Viruses-basel,2015,7(5):2668-2682. |
| APA | Li, Jing,Yu, Meng,Zheng, Weinan,&Liu, Wenjun.(2015).Nucleocytoplasmic shuttling of influenza a virus proteins.Viruses-basel,7(5),2668-2682. |
| MLA | Li, Jing,et al."Nucleocytoplasmic shuttling of influenza a virus proteins".Viruses-basel 7.5(2015):2668-2682. |
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