Host cell targets of tegument protein vp22 of herpes simplex virus 1 | |
Li, Meili1; Wang, Lin1; Ren, Xiaoming2; Zheng, Chunfu1 | |
刊名 | Archives of virology
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2011-06-01 | |
卷号 | 156期号:6页码:1079-1084 |
ISSN号 | 0304-8608 |
DOI | 10.1007/s00705-011-0960-9 |
通讯作者 | Zheng, chunfu(zheng.alan@hotmail.com) |
英文摘要 | In the present study, seven novel host cell factors associated with vp22 were identified from the human leukocyte cdna library using a yeast two-hybrid high-throughput screening system. to confirm some of the interactions, vp22 and its homologues and two candidate targets were tagged with enhanced cyan or yellow fluorescent protein. while ring finger protein 10 (rnf10), wd repeat-containing protein 42a (wdr42a) or vp22 alone showed distinct subcellular localization patterns, rnf10 and wdr42a were relocated when co-expressed with vp22 or its homologues. thus, these potential host cell factors of vp22 might expand the list of the host targets of vp22. |
WOS关键词 | MICROTUBULE REORGANIZATION ; BOVINE HERPESVIRUS-1 ; NUCLEAR-LOCALIZATION ; OXIDATIVE STRESS ; TYPE-1 ; VP16 ; INFECTION ; INTERACTS ; RING ; TRANSCRIPTION |
WOS研究方向 | Virology |
WOS类目 | Virology |
语种 | 英语 |
出版者 | SPRINGER WIEN |
WOS记录号 | WOS:000291056700020 |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/2375901 |
专题 | 武汉病毒研究所 |
通讯作者 | Zheng, Chunfu |
作者单位 | 1.Chinese Acad Sci, State Key Lab Virol, Wuhan Inst Virol, Wuhan 430071, Peoples R China 2.Beijing Agr Coll, Dept Vet Med, Beijing 102206, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Meili,Wang, Lin,Ren, Xiaoming,et al. Host cell targets of tegument protein vp22 of herpes simplex virus 1[J]. Archives of virology,2011,156(6):1079-1084. |
APA | Li, Meili,Wang, Lin,Ren, Xiaoming,&Zheng, Chunfu.(2011).Host cell targets of tegument protein vp22 of herpes simplex virus 1.Archives of virology,156(6),1079-1084. |
MLA | Li, Meili,et al."Host cell targets of tegument protein vp22 of herpes simplex virus 1".Archives of virology 156.6(2011):1079-1084. |
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