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Host cell targets of tegument protein vp22 of herpes simplex virus 1
Li, Meili1; Wang, Lin1; Ren, Xiaoming2; Zheng, Chunfu1
刊名Archives of virology
2011-06-01
卷号156期号:6页码:1079-1084
ISSN号0304-8608
DOI10.1007/s00705-011-0960-9
通讯作者Zheng, chunfu(zheng.alan@hotmail.com)
英文摘要In the present study, seven novel host cell factors associated with vp22 were identified from the human leukocyte cdna library using a yeast two-hybrid high-throughput screening system. to confirm some of the interactions, vp22 and its homologues and two candidate targets were tagged with enhanced cyan or yellow fluorescent protein. while ring finger protein 10 (rnf10), wd repeat-containing protein 42a (wdr42a) or vp22 alone showed distinct subcellular localization patterns, rnf10 and wdr42a were relocated when co-expressed with vp22 or its homologues. thus, these potential host cell factors of vp22 might expand the list of the host targets of vp22.
WOS关键词MICROTUBULE REORGANIZATION ; BOVINE HERPESVIRUS-1 ; NUCLEAR-LOCALIZATION ; OXIDATIVE STRESS ; TYPE-1 ; VP16 ; INFECTION ; INTERACTS ; RING ; TRANSCRIPTION
WOS研究方向Virology
WOS类目Virology
语种英语
出版者SPRINGER WIEN
WOS记录号WOS:000291056700020
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2375901
专题武汉病毒研究所
通讯作者Zheng, Chunfu
作者单位1.Chinese Acad Sci, State Key Lab Virol, Wuhan Inst Virol, Wuhan 430071, Peoples R China
2.Beijing Agr Coll, Dept Vet Med, Beijing 102206, Peoples R China
推荐引用方式
GB/T 7714
Li, Meili,Wang, Lin,Ren, Xiaoming,et al. Host cell targets of tegument protein vp22 of herpes simplex virus 1[J]. Archives of virology,2011,156(6):1079-1084.
APA Li, Meili,Wang, Lin,Ren, Xiaoming,&Zheng, Chunfu.(2011).Host cell targets of tegument protein vp22 of herpes simplex virus 1.Archives of virology,156(6),1079-1084.
MLA Li, Meili,et al."Host cell targets of tegument protein vp22 of herpes simplex virus 1".Archives of virology 156.6(2011):1079-1084.
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