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	Characterization of h5n1 influenza viruses isolated from migratory birds in qinghai province of china in 2006
	Lei, Fumin; Tang, Shuang; Zhao, Delong; Zhang, Xiaowei; Kou, Zheng; Li, Yongdong; Zhang, Zhong; Yin, Zuohua; Chen, Shengliang; Li, Sandan
刊名	Avian diseases
	2007-06-01
卷号	51期号:2页码:568-572
关键词	Influenza virus H5n1 subtype Migrating birds
ISSN号	0005-2086
通讯作者	Li, tianxian(litx@wh.iov.cn)
英文摘要	Avian influenza h5n1 viruses pose a significant threat to human health because of their ability to infect humans directly. in the paper, three highly pathogenic h5n1 influenza viruses were isolated from three species of migratory birds in qinghai province of china in 2006. the analysis of the genome sequences indicated that the three isolates shared high homology with each other (94% to 99%). three isolates shared a common ancestor and were closest to strains isolated from qinghai and siberia in 2005, but distinct from poultry viruses found in southeast asia. in experimental infection, all three viruses were highly pathogenic to chickens and mice. the results suggest that highly pathogenic avian influenza h5n1 viruses still exist in the migratory birds and could spread to other regions with wild bird migration.
WOS关键词	AVIAN INFLUENZA ; A VIRUSES ; ASIA ; VIRULENCE ; WATERFOWL ; OUTBREAK
WOS研究方向	Veterinary Sciences
WOS类目	Veterinary Sciences
语种	英语
出版者	AMER ASSOC AVIAN PATHOLOGISTS
WOS记录号	WOS:000247088700009
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2375373
专题	武汉病毒研究所
通讯作者	Li, Tianxian
作者单位	1.Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China 2.Chinese Acad Sci, Inst Zool, Beijing 100080, Peoples R China 3.Chinese Acad Sci, Beijing Genom Inst, Beijing 101300, Peoples R China 4.Forestry Adm Qinghai Prov, Xining 810007, Peoples R China 5.Chinese Acad Sci, Informat Ctr Comp Network, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Lei, Fumin,Tang, Shuang,Zhao, Delong,et al. Characterization of h5n1 influenza viruses isolated from migratory birds in qinghai province of china in 2006[J]. Avian diseases,2007,51(2):568-572.
APA	Lei, Fumin.,Tang, Shuang.,Zhao, Delong.,Zhang, Xiaowei.,Kou, Zheng.,...&Li, Tianxian.(2007).Characterization of h5n1 influenza viruses isolated from migratory birds in qinghai province of china in 2006.Avian diseases,51(2),568-572.
MLA	Lei, Fumin,et al."Characterization of h5n1 influenza viruses isolated from migratory birds in qinghai province of china in 2006".Avian diseases 51.2(2007):568-572.

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