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	Rapid identification of bacteria by membrane-responsive aggregation of a pyrene derivative
	Long, Shuangshuang1,2; Miao, Lu1; Li, Ruihua3; Deng, Fei1,2; Qaao, Qinglong1; Liu, Xiaogang5; Yan, Aixin4; Xu, Zhaochao1
刊名	Acs sensors
	2019-02-01
卷号	4期号:2页码:281-285
关键词	Bacteria identification Multidrug resistant Pyrene derivative Aggregation Rapid identification
ISSN号	2379-3694
DOI	10.1021/acssensors.8b01466
通讯作者	Xu, zhaochao(zcxu@dicp.ac.cn)
英文摘要	An imidazolium-derived pyrene aggregation was developed to rapidly identify and quantify different bacteria species. when the nonemissive aggregates bound to the anionic bacteria surface, the sensor disassembled to turn on significant fluorescence. at the same time, ratiometric signals between pyrene monomer and excimer emission were controlled by different interactions with various bacteria surfaces. the resulted different fluorescent emission profiles then were obtained as fingerprints for various bacterial species. by converting emission profiles directly into output signals of two channels, fluorescence increase and ratiometric change, a two-dimensional analysis map was generated for bacteria identification. we demonstrated that our sensor rapidly identified 10 species of bacteria and 14 clinical isolated multidrug-resistant bacteria, and we determined their staining properties (gram-positive or gram-negative).
WOS关键词	SENSOR ARRAY ; DISCRIMINATION ; NANOPARTICLES ; MECHANISMS ; MICELLES ; CHARGES ; POLYMER
WOS研究方向	Chemistry ; Science & Technology - Other Topics
WOS类目	Chemistry, Multidisciplinary ; Chemistry, Analytical ; Nanoscience & Nanotechnology
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000459836400003
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2372684
专题	大连化学物理研究所
通讯作者	Xu, Zhaochao
作者单位	1.Chinese Acad Sci, CAS Key Lab Separat Sci Analyt Chem, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Dalian Med Univ, Affiliated Hosp 2, Dalian 116023, Peoples R China 4.Univ Hong Kong, Sch Biol Sci, Hong Kong, Peoples R China 5.Singapore Univ Technol & Design, Singapore 487372, Singapore
推荐引用方式 GB/T 7714	Long, Shuangshuang,Miao, Lu,Li, Ruihua,et al. Rapid identification of bacteria by membrane-responsive aggregation of a pyrene derivative[J]. Acs sensors,2019,4(2):281-285.
APA	Long, Shuangshuang.,Miao, Lu.,Li, Ruihua.,Deng, Fei.,Qaao, Qinglong.,...&Xu, Zhaochao.(2019).Rapid identification of bacteria by membrane-responsive aggregation of a pyrene derivative.Acs sensors,4(2),281-285.
MLA	Long, Shuangshuang,et al."Rapid identification of bacteria by membrane-responsive aggregation of a pyrene derivative".Acs sensors 4.2(2019):281-285.

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