Preparation, structural characterization and in vitro antitumor activity of kappa-carrageenan oligosaccharide fraction from Kappaphycus striatum | |
Yuan, HM![]() ![]() | |
刊名 | JOURNAL OF APPLIED PHYCOLOGY
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2005 | |
卷号 | 17期号:1页码:7-13 |
关键词 | Kappa-carrageenan Kappaphycus Striatum Oligosaccharides Antitumor |
ISSN号 | 0921-8971 |
DOI | 10.1007/s10811-005-5513-8 |
文献子类 | Article |
英文摘要 | Oligosaccharides were prepared through mild hydrochloric acid hydrolysis of kappa-carrageenan from Kappaphycus striatum to compare the antitumor activity with carrageenan polysaccharides. Oligosaccharide fractions were isolated by gel permeation chromatography and the structure of fraction 1 (F1) was studied by using negative- ion electrospray ionization-mass spectrometry (ESI-MS), and H-1 and C-13-NMR spectrometry. The in vitro antitumor effects in three human neoplastic cell lines (KB, BGC, and Hela) of polysaccharides and F1 were investigated. The bioassay results showed that F1 exhibited relatively higher antitumor activity against the three cancer cells than polysaccharides.; Oligosaccharides were prepared through mild hydrochloric acid hydrolysis of kappa-carrageenan from Kappaphycus striatum to compare the antitumor activity with carrageenan polysaccharides. Oligosaccharide fractions were isolated by gel permeation chromatography and the structure of fraction 1 (F1) was studied by using negative- ion electrospray ionization-mass spectrometry (ESI-MS), and H-1 and C-13-NMR spectrometry. The in vitro antitumor effects in three human neoplastic cell lines (KB, BGC, and Hela) of polysaccharides and F1 were investigated. The bioassay results showed that F1 exhibited relatively higher antitumor activity against the three cancer cells than polysaccharides. |
学科主题 | Biotechnology & Applied Microbiology ; Marine & Freshwater Biology |
URL标识 | 查看原文 |
语种 | 英语 |
WOS记录号 | WOS:000229904700002 |
公开日期 | 2010-12-22 |
内容类型 | 期刊论文 |
源URL | [http://ir.qdio.ac.cn/handle/337002/2707] ![]() |
专题 | 海洋研究所_海洋生态与环境科学重点实验室 海洋研究所_海洋地质与环境重点实验室 |
作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
推荐引用方式 GB/T 7714 | Yuan, HM,Song, JM. Preparation, structural characterization and in vitro antitumor activity of kappa-carrageenan oligosaccharide fraction from Kappaphycus striatum[J]. JOURNAL OF APPLIED PHYCOLOGY,2005,17(1):7-13. |
APA | Yuan, HM,&Song, JM.(2005).Preparation, structural characterization and in vitro antitumor activity of kappa-carrageenan oligosaccharide fraction from Kappaphycus striatum.JOURNAL OF APPLIED PHYCOLOGY,17(1),7-13. |
MLA | Yuan, HM,et al."Preparation, structural characterization and in vitro antitumor activity of kappa-carrageenan oligosaccharide fraction from Kappaphycus striatum".JOURNAL OF APPLIED PHYCOLOGY 17.1(2005):7-13. |
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