C-coordinated O-carboxymethyl chitosan metal complexes: Synthesis, characterization and antifungal efficacy

doi:10.1016/j.ijbiomac.2017.07.176

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	C-coordinated O-carboxymethyl chitosan metal complexes: Synthesis, characterization and antifungal efficacy
	Liu, Weixiang 1,2; Qin, Yukun 1; Liu, Song 1; Xing, Ronge1 ; Yu, Huahua1 ; Chen, Xiaolin 1; Li, Kecheng 1; Li, Pengcheng1
刊名	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
	2018
卷号	106 页码:68-77
关键词	Coordination Chitosan Metal Complex Antifungal
DOI	10.1016/j.ijbiomac.2017.07.176
文献子类	Article
英文摘要	A novel type of O-carboxymethyl chitosan Schiff bases (O-CSPX) was synthesized via a condensation reaction. After the coordination reaction of cupric ions, zinc ions and nickel ions, metal complexes (O-CSPX-M) were achieved. The theoretical structure of O-CSPX-M calculated by Gaussian 09 reveals that the copper ions and nickel ions underwent dsp(2) hybridization, the zinc ions underwent spa hybridization, and they all coordinated by the carbon atom in the p-pi conjugate group. Then, the structures were confirmed by FT-IR, H-1 NMR, CP-MAS C-13 NMR, elemental analysis, DSC and XRD. The antifungal properties of O-CSPX-M against Phytophthora capsici (P. capsici), Gibberella zeae (G. zeae), Fusarium oxysporum (F. oxysporum) and Botrytis cinerea (B. cinerea) were evaluated at concentrations ranging from 0.05 mg/mL to 0.40 mg/mL. The experiments indicated that the derivatives have significantly enhanced antifungal activity after metal ions complexation compared with the original chitosan. Moreover, it was shown that 0.20 mg/mL of O-CSPX-Cu can 100% inhibit the growth of P. capsici and 0.20 mg/mL of O-CSPX-Ni can 87.5% inhibit the growth of B. cinerea. In addition, the phytotoxicity assay and cell viability assay were also evaluated. The experimental results may provide a novel direction for the development of metal fungicides. (C) 2017 Published by Elsevier B.V.
语种	英语
WOS记录号	WOS:000417661600008
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.qdio.ac.cn/handle/337002/154316]
专题	海洋研究所_实验海洋生物学重点实验室海洋研究所_海洋生物技术研发中心海洋研究所_海洋环境工程技术研究发展中心
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Liu, Weixiang,Qin, Yukun,Liu, Song,et al. C-coordinated O-carboxymethyl chitosan metal complexes: Synthesis, characterization and antifungal efficacy[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2018,106:68-77.
APA	Liu, Weixiang.,Qin, Yukun.,Liu, Song.,Xing, Ronge.,Yu, Huahua.,...&Li, Pengcheng.(2018).C-coordinated O-carboxymethyl chitosan metal complexes: Synthesis, characterization and antifungal efficacy.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,106,68-77.
MLA	Liu, Weixiang,et al."C-coordinated O-carboxymethyl chitosan metal complexes: Synthesis, characterization and antifungal efficacy".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 106(2018):68-77.