Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins

	Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins
	Wang, Liang-Liang; Jiang, Ting; Li, Peng-Hua; Sun, Rou-Jing; Zuo, Zhili
刊名	ADVANCED SYNTHESIS & CATALYSIS
	2018
卷号	360 期号:24 页码:4832-4836
ISSN号	1615-4150
英文摘要	A variety of enantioenriched 3-N-substituted spirooxindole-dihydroquinazolinones were synthesized by cyclization reactions involving 2-amino-N-substituted benzamides and isatins catalyzed by SPINOL-CPA catalyst in a highly enantioselective manner with excellent ee values (up to 99%) and good yields (up to 99%). So far, this is the first example to directly access this type of chiral pharmaceutically privileged 3-N-substituted dihydroquinazolinone derivatives with a broad substrate scope.
语种	英语
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/64658]
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Wang, Liang-Liang,Jiang, Ting,Li, Peng-Hua,et al. Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins[J]. ADVANCED SYNTHESIS & CATALYSIS,2018,360(24):4832-4836.
APA	Wang, Liang-Liang,Jiang, Ting,Li, Peng-Hua,Sun, Rou-Jing,&Zuo, Zhili.(2018).Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins.ADVANCED SYNTHESIS & CATALYSIS,360(24),4832-4836.
MLA	Wang, Liang-Liang,et al."Asymmetric Syntheses of Spirooxindole-dihydroquinazolinones by Cyclization Reactions between N-substituted Anthranilamides and Isatins".ADVANCED SYNTHESIS & CATALYSIS 360.24(2018):4832-4836.