Nitric oxide inhibits larval settlement in Amphibalanus amphitrite cyprids by repressing muscle locomotion and molting

doi:10.1002/pmic.201500112

CORC > 深海科学与工程研究所 > 中国科学院深海科学与工程研究所 > 深海科学研究部 > 深海生物学研究室 > 深海生物蛋白质组学及分子生物学研究组

	Nitric oxide inhibits larval settlement in Amphibalanus amphitrite cyprids by repressing muscle locomotion and molting
	Xu, Ying 4; He, Li-Sheng1 ; Qian, Pei-Yuan 2,3; Zhang, Yu 4; Wong, Yue-Him 3; Zhang, Gen 2,3
刊名	PROTEOMICS
	2015-11-01
卷号	15 期号:22 页码:3854-3864
关键词	Animal Proteomics Barnacle Label-free Quantification Ms Nitric Oxide
DOI	10.1002/pmic.201500112
文献子类	Article
英文摘要	Nitric oxide (NO) is a universal signaling molecule and plays a negative role in the metamorphosis of many biphasic organisms. Recently, the NO/cGMP (cyclic guanosine monophosphate) signaling pathway was reported to repress larval settlement in the barnacle Amphibalanus amphitrite. To understand the underlying molecular mechanism, we analyzed changes in the proteome of A. amphitrite cyprids in response to different concentrations of the NO donor sodium nitroprusside (SNP; 62.5, 250, and 1000 mu M) using a label-free proteomics method. Compared with the control, the expression of 106 proteins differed in all three treatments. These differentially expressed proteins were assigned to 13 pathways based on KEGG pathway enrichment analysis. SNP treatment stimulated the expression of heat shock proteins and arginine kinase, which are functionally related to NO synthases, increased the expression levels of glutathione transferases for detoxification, and activated the iron-mediated fatty acid degradation pathway and the citrate cycle through ferritin. Moreover, NO repressed the level of myosins and cuticular proteins, which indicated that NO might inhibit larval settlement in A. amphitrite by modulating the process of muscle locomotion and molting.
WOS关键词	SNAIL ILYANASSA-OBSOLETA ; PROGRAMMED CELL-DEATH ; SMOOTH-MUSCLE ; CREPIDULA-FORNICATA ; OXIDATIVE STRESS ; NERVOUS-SYSTEM ; L-ARGININE ; METAMORPHOSIS ; SYNTHASE ; IRON
语种	英语
WOS记录号	WOS:000367727800010
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.idsse.ac.cn/handle/183446/1343]
专题	深海科学研究部_深海生物学研究室_深海生物蛋白质组学及分子生物学研究组
作者单位	1.Chinese Acad Sci, Sanya Inst Deep Sea Sci & Engn, Sanya City, Hainan Province, Peoples R China 2.Hong Kong Univ Sci & Technol, Environm Sci Programs, Sch Sci, Kowloon, Hong Kong, Peoples R China 3.Hong Kong Univ Sci & Technol, Div Life Sci, KAUST Global Collaborat Res Program, Kowloon, Hong Kong, Peoples R China 4.Shenzhen Univ, Coll Life Sci, Shenzhen Key Lab Marine Bioresource & Ecoenvironm, Shenzhen, Peoples R China
推荐引用方式 GB/T 7714	Xu, Ying,He, Li-Sheng,Qian, Pei-Yuan,et al. Nitric oxide inhibits larval settlement in Amphibalanus amphitrite cyprids by repressing muscle locomotion and molting[J]. PROTEOMICS,2015,15(22):3854-3864.
APA	Xu, Ying,He, Li-Sheng,Qian, Pei-Yuan,Zhang, Yu,Wong, Yue-Him,&Zhang, Gen.(2015).Nitric oxide inhibits larval settlement in Amphibalanus amphitrite cyprids by repressing muscle locomotion and molting.PROTEOMICS,15(22),3854-3864.
MLA	Xu, Ying,et al."Nitric oxide inhibits larval settlement in Amphibalanus amphitrite cyprids by repressing muscle locomotion and molting".PROTEOMICS 15.22(2015):3854-3864.