A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata
Liu, Xin; Tang, Gui-Hua; Weng, Han-Zhuang; Zhang, Jun-Sheng; Xu, You-Kai; Yin, Sheng4
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
2018
卷号20期号:12页码:1123-1128
关键词Phosphodiesterase-4 Inhibitors Natural Pigment Tamariscina
ISSN号1028-6020
DOI10.1080/10286020.2017.1378646
英文摘要

Five selaginellin derivatives (1 and 3-6) including a new one, selaginellin T (1), and a new triarylbenzophenone analog, selagibenzophenone A (2), were isolated from the whole plants of Selaginella pulvinata. Their structures were determined by 1D- and 2D-NMR and HR-ESI-MS data. Selagibenzophenone A (2) is the first example of naturally occurring triarylbenzophenone. The results of the phosphodiesterase-4 (PDE4) inhibitory screening assays showed that compounds 1-6 exhibited potent activities with the IC50 values in the range of 1.04-9.35 mu M. [GRAPHICS] .

学科主题Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000459882800004
内容类型期刊论文
源URL[http://ir.xtbg.org.cn/handle/353005/11247]  
专题西双版纳热带植物园_民族植物学研究组
作者单位1.[Liu, Xin
2.Tang, Gui-Hua
3.Weng, Han-Zhuang
4.Zhang, Jun-Sheng
5.Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China
6.Chinese Acad Sci, Key Lab Trop Plant Resource & Sustainable Use, Xishuangbanna Trop Bot Garden, Menglun 666303, Peoples R China
推荐引用方式
GB/T 7714
Liu, Xin,Tang, Gui-Hua,Weng, Han-Zhuang,et al. A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2018,20(12):1123-1128.
APA Liu, Xin,Tang, Gui-Hua,Weng, Han-Zhuang,Zhang, Jun-Sheng,Xu, You-Kai,&Yin, Sheng.(2018).A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,20(12),1123-1128.
MLA Liu, Xin,et al."A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 20.12(2018):1123-1128.
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