A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata | |
Liu, Xin; Tang, Gui-Hua; Weng, Han-Zhuang; Zhang, Jun-Sheng; Xu, You-Kai; Yin, Sheng4 | |
刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH |
2018 | |
卷号 | 20期号:12页码:1123-1128 |
关键词 | Phosphodiesterase-4 Inhibitors Natural Pigment Tamariscina |
ISSN号 | 1028-6020 |
DOI | 10.1080/10286020.2017.1378646 |
英文摘要 | Five selaginellin derivatives (1 and 3-6) including a new one, selaginellin T (1), and a new triarylbenzophenone analog, selagibenzophenone A (2), were isolated from the whole plants of Selaginella pulvinata. Their structures were determined by 1D- and 2D-NMR and HR-ESI-MS data. Selagibenzophenone A (2) is the first example of naturally occurring triarylbenzophenone. The results of the phosphodiesterase-4 (PDE4) inhibitory screening assays showed that compounds 1-6 exhibited potent activities with the IC50 values in the range of 1.04-9.35 mu M. [GRAPHICS] . |
学科主题 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
语种 | 英语 |
WOS记录号 | WOS:000459882800004 |
内容类型 | 期刊论文 |
源URL | [http://ir.xtbg.org.cn/handle/353005/11247] |
专题 | 西双版纳热带植物园_民族植物学研究组 |
作者单位 | 1.[Liu, Xin 2.Tang, Gui-Hua 3.Weng, Han-Zhuang 4.Zhang, Jun-Sheng 5.Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China 6.Chinese Acad Sci, Key Lab Trop Plant Resource & Sustainable Use, Xishuangbanna Trop Bot Garden, Menglun 666303, Peoples R China |
推荐引用方式 GB/T 7714 | Liu, Xin,Tang, Gui-Hua,Weng, Han-Zhuang,et al. A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2018,20(12):1123-1128. |
APA | Liu, Xin,Tang, Gui-Hua,Weng, Han-Zhuang,Zhang, Jun-Sheng,Xu, You-Kai,&Yin, Sheng.(2018).A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,20(12),1123-1128. |
MLA | Liu, Xin,et al."A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 20.12(2018):1123-1128. |
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