Occurrence of antibiotic resistance genes and mobile genetic elements in enterococci and genomic DNA during anaerobic digestion of pharmaceutical waste sludge with different pretreatments

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 大气污染控制中心

	Occurrence of antibiotic resistance genes and mobile genetic elements in enterococci and genomic DNA during anaerobic digestion of pharmaceutical waste sludge with different pretreatments
	Wei, Yuansong; Chen, Meixue; Tong, Juan; Lu, XueTing; Zhang, JunYa; Sui, Qianwen; Wang, Rui
刊名	BIORESOURCE TECHNOLOGY
	2017-07-01
卷号	235 期号:0 页码:316-324
关键词	Antibiotic Resistance Enterococci Pharmaceutical Waste Sludge Anaerobic Digestion Pretreatment
英文摘要	Pharmaceutical waste sludge harbors large amounts of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs), and it is necessary to study the reduction of ARGs and MGEs during sludge treatment. Therefore, the antibiotic resistance phenotypes and genotypes of enterococci, and the ARGs and MGEs in genomic DNA were investigated during anaerobic digestion (AD) with microwave (MW), thermal hydrolysis (TH) and ozone pretreatment. Results showed that sludge pretreatment increased the occurrence of the resistance phenotypes and genotypes of enterococci. During AD, the resistance of enterococci to macrolides decreased, except for in the MW-pretreated sludge. Horizontal gene transfer and co-occurrence of ermB and tetM in enterococci resulted in increased tetracycline resistance of enterococci throughout the sludge treatment. MGEs such as intI1, ISCR1 and Tn916/1545 had a significant effect on the distribution of ARGs. AD with pretreatment, especially TH pretreatment, resulted in greater ARGs and MGEs reduction and improved methane production. (C) 2017 Published by Elsevier Ltd.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/39206]
专题	生态环境研究中心_大气污染控制中心
推荐引用方式 GB/T 7714	Wei, Yuansong,Chen, Meixue,Tong, Juan,et al. Occurrence of antibiotic resistance genes and mobile genetic elements in enterococci and genomic DNA during anaerobic digestion of pharmaceutical waste sludge with different pretreatments[J]. BIORESOURCE TECHNOLOGY,2017,235(0):316-324.
APA	Wei, Yuansong.,Chen, Meixue.,Tong, Juan.,Lu, XueTing.,Zhang, JunYa.,...&Wang, Rui.(2017).Occurrence of antibiotic resistance genes and mobile genetic elements in enterococci and genomic DNA during anaerobic digestion of pharmaceutical waste sludge with different pretreatments.BIORESOURCE TECHNOLOGY,235(0),316-324.
MLA	Wei, Yuansong,et al."Occurrence of antibiotic resistance genes and mobile genetic elements in enterococci and genomic DNA during anaerobic digestion of pharmaceutical waste sludge with different pretreatments".BIORESOURCE TECHNOLOGY 235.0(2017):316-324.